SCOPe 2.08: Domain d6av2b_: 6av2 B:

Lineage for d6av2b_ (6av2 B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.174: Nitric oxide (NO) synthase oxygenase domain [56511] (1 superfamily)
   unusual fold

4. Superfamily d.174.1: Nitric oxide (NO) synthase oxygenase domain [56512] (1 family)
   automatically mapped to Pfam PF02898

5. Family d.174.1.1: Nitric oxide (NO) synthase oxygenase domain [56513] (2 proteins)

6. Protein automated matches [190421] (6 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187302] (89 PDB entries)

8. Domain d6av2b_: 6av2 B: [354522]
   automated match to d4ucha_
   complexed with by7, h4b, hem, zn; mutant

Details for d6av2b_

PDB Entry: 6av2, 2.1 Å

PDB Description: structure of human neuronal nitric oxide synthase r354a/g357d mutant heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-5- (trifluoromethyl)phenethyl)-4-methylpyridin-2-amine

PDB Compounds: (B:) Nitric oxide synthase, brain

SCOPe Domain Sequences for d6av2b_:

Sequence, based on SEQRES records:

>d6av2b_ d.174.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rflkvknwetevvltdtlhlkstletgcteyicmgsimhpsqharrpedvatkdqlfpla
kefidqyyssikrfgskahmerleevnkeidttstyqlkdteliygakhawrnasrcvgr
iqwsklqvfdardcttahgmfnyicnhvkyatnkgnlrsaitifpqrtdgkhdfrvwnsq
liryagykqpdgstlgdpanvqfteiciqqgwkpprgrfdvlplllqangndpelfqipp
elvlevpirhpkfewfkdlglkwyglpavsnmlleigglefsacpfsgwymgteigvrdy
cdnsrynileevakkmnldmrktsslwkdqalveiniavlysfqsdkvtivdhhsatesf
ikhmeneyrcrggcpadwvwivppmsgsitpvfhqemlnyrltpsfeyqpdpwnthvw

Sequence, based on observed residues (ATOM records):

>d6av2b_ d.174.1.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rflkvknwetevvltdtlhlkstletgcteyicmgsimhpsatkdqlfplakefidqyys
sikrfgskahmerleevnkeidttstyqlkdteliygakhawrnasrcvgriqwsklqvf
dardcttahgmfnyicnhvkyatnkgnlrsaitifpqrtdgkhdfrvwnsqliryagykq
pdgstlgdpanvqfteiciqqgwkpprgrfdvlplllqangndpelfqippelvlevpir
hpkfewfkdlglkwyglpavsnmlleigglefsacpfsgwymgteigvrdycdnsrynil
eevakkmnldmrktsslwkdqalveiniavlysfqsdkvtivdhhsatesfikhmeneyr
crggcpadwvwivppmsgsitpvfhqemlnyrltpsfeyqpdpwnthvw

Timeline for d6av2b_:

• d6av2b_ first appeared in SCOPe 2.07