SCOPe 2.08: Domain d5yzhb_: 5yzh B:

Lineage for d5yzhb_ (5yzh B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.77: Isocitrate/Isopropylmalate dehydrogenase-like [53658] (1 superfamily)
   consists of two intertwined (sub)domains related by pseudo dyad; duplication
   3 layers: a/b/a; single mixed beta-sheet of 10 strands, order 213A945867 (A=10); strands from 5 to 9 are antiparallel to the rest

4. Superfamily c.77.1: Isocitrate/Isopropylmalate dehydrogenase-like [53659] (6 families)
   the constituent families form similar dimers

5. Family c.77.1.1: Dimeric isocitrate & isopropylmalate dehydrogenases [53660] (4 proteins)
   the active site is between the two identical subunits

6. Protein automated matches [190072] (22 species)
   not a true protein

7. Species Mouse (Mus musculus) [TaxId:10090] [187557] (3 PDB entries)

8. Domain d5yzhb_: 5yzh B: [354414]
   automated match to d1t0la_
   complexed with gol, nap

Details for d5yzhb_

PDB Entry: 5yzh, 1.99 Å

PDB Description: crystal structure of mouse cytosolic isocitrate dehydrogenase

PDB Compounds: (B:) isocitrate dehydrogenase [nadp] cytoplasmic

SCOPe Domain Sequences for d5yzhb_:

Sequence; same for both SEQRES and ATOM records:

>d5yzhb_ c.77.1.1 (B:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
kiqggsvvemqgdemtriiwelikeklilpyveldlhsydlgienrdatndqvtkdaaea
ikkynvgvkcatitpdekrveefklkqmwkspngtirnilggtvfreaiickniprlvtg
wvkpiiigrhaygdqyratdfvvpgpgkveitytpkdgtqkvtymvhdfeegggvamgmy
nqdksiedfahssfqmalskgwplylstkntilkkydgrfkdifqeiydkkyksqfeaqk
icyehrliddmvaqamkseggfiwacknydgdvqsdsvaqgygslgmmtsvlicpdgktv
eaeaahgtvtrhyrmyqkgqetstnpiasifawsrglahrakldnntelsffakaledvc
ietieagfmtkdlaacikglpnvqrsdylntfefmdklgenlkaklaqa

Timeline for d5yzhb_:

• d5yzhb_ first appeared in SCOPe 2.07