Lineage for d6c1sa2 (6c1s A:357-522)

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2368400Fold b.7: C2 domain-like [49561] (5 superfamilies)
    sandwich; 8 strands in 2 sheets; greek-key
  4. 2368401Superfamily b.7.1: C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (3 families) (S)
    two constituent families are related by circular permutation
  5. 2368402Family b.7.1.1: PLC-like (P variant) [49563] (12 proteins)
  6. 2368425Protein Phoshoinositide 3-kinase (PI3K) [49570] (2 species)
  7. 2368426Species Human (Homo sapiens) [TaxId:9606] [49572] (70 PDB entries)
  8. 3053788Domain d6c1sa2: 6c1s A:357-522 [353850]
    Other proteins in same PDB: d6c1sa1, d6c1sa3, d6c1sa4
    automated match to d1he8a2
    complexed with efv, so4

Details for d6c1sa2

PDB Entry: 6c1s (more details), 2.31 Å

PDB Description: phosphoinositide 3-kinase gamma bound to an pyrrolopyridinone inhibitor
PDB Compounds: (A:) Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

SCOPe Domain Sequences for d6c1sa2:

Sequence, based on SEQRES records: (download)

>d6c1sa2 b.7.1.1 (A:357-522) Phoshoinositide 3-kinase (PI3K) {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d6c1sa2 b.7.1.1 (A:357-522) Phoshoinositide 3-kinase (PI3K) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d6c1sa2:

Click to download the PDB-style file with coordinates for d6c1sa2.
(The format of our PDB-style files is described here.)

Timeline for d6c1sa2:

  • d6c1sa2 is new in SCOPe 2.07-stable