SCOPe 2.08: Domain d6gq7a1: 6gq7 A:146-320

Lineage for d6gq7a1 (6gq7 A:146-320)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.15: beta-Grasp (ubiquitin-like) [54235] (15 superfamilies)
   core: beta(2)-alpha-beta(2); mixed beta-sheet 2143

4. Superfamily d.15.1: Ubiquitin-like [54236] (11 families)

5. Family d.15.1.5: Ras-binding domain, RBD [54263] (14 proteins)
   contains Pfam PF00788 and Pfam PF02196

6. Protein Phoshoinositide 3-kinase (PI3K) [54274] (2 species)
   includes parts of the flanking linkers

7. Species Human (Homo sapiens) [TaxId:9606] [54276] (77 PDB entries)

8. Domain d6gq7a1: 6gq7 A:146-320 [353812]
   Other proteins in same PDB: d6gq7a2, d6gq7a3
   automated match to d1he8a3
   complexed with dd8
   has additional insertions and/or extensions that are not grouped together

Details for d6gq7a1

PDB Entry: 6gq7, 2.84 Å

PDB Description: pi3kg in complex with inh

PDB Compounds: (A:) Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

SCOPe Domain Sequences for d6gq7a1:

Sequence, based on SEQRES records:

>d6gq7a1 d.15.1.5 (A:146-320) Phoshoinositide 3-kinase (PI3K) {Human (Homo sapiens) [TaxId: 9606]}
esqafqrqltaligydvtdvsnvhddeleftrrglvtprmaevasrdpklyamhpwvtsk
plpeylwkkianncifivihrsttsqtikvspddtpgailqsfftkmakkkslmdipesq
seqdfvlrvcgrdeylvgetpiknfqwvrhclkngeeihvvldtppdpaldevrk

Sequence, based on observed residues (ATOM records):

>d6gq7a1 d.15.1.5 (A:146-320) Phoshoinositide 3-kinase (PI3K) {Human (Homo sapiens) [TaxId: 9606]}
esqafqrqltaligydvtdvsnvhddeleftrrglvtprmaevasrdpklyamhpwvtsk
plpeylwkkianncifivihrttsqtikvspddtpgailqdfvlrvcgrdeylvgetpik
nfqwvrhclkngeeihvvldtppdpaldevrk

Timeline for d6gq7a1:

• d6gq7a1 first appeared in SCOPe 2.07