SCOPe 2.08: Domain d5nzzg_: 5nzz G:

Lineage for d5nzzg_ (5nzz G:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein MAP kinase p38 [56129] (2 species)
   CMGC group; ERK/MAPK subfamily; serine/threonine kinase

7. Species Mouse (Mus musculus) [TaxId:10090] [56131] (111 PDB entries)

8. Domain d5nzzg_: 5nzz G: [353091]
   automated match to d1leza_
   complexed with ags, mg, ni

Details for d5nzzg_

PDB Entry: 5nzz, 2.6 Å

PDB Description: crystal structure of phosphorylated p38amapk in complex with tab1

PDB Compounds: (G:) Mitogen-activated protein kinase 14

SCOPe Domain Sequences for d5nzzg_:

Sequence, based on SEQRES records:

>d5nzzg_ d.144.1.7 (G:) MAP kinase p38 {Mouse (Mus musculus) [TaxId: 10090]}
rptfyrqelnktiwevperyqnlspvgsgaygsvcaafdtktghrvavkklsrpfqsiih
akrtyrelrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqkltd
dhvqfliyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemtgyva
trwyrapeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpga
ellkkissesarnyiqslaqmpkmnfanvfiganplavdllekmlvldsdkritaaqala
hayfaqyhdpddepvadpydqsfesrdllidewksltydevisfvpppl

Sequence, based on observed residues (ATOM records):

>d5nzzg_ d.144.1.7 (G:) MAP kinase p38 {Mouse (Mus musculus) [TaxId: 10090]}
rptfyrqelnktiwevperyqnlspvgsvcaafdtktghrvavkklsrpfqsiihakrty
relrllkhmkhenviglldvftparsleefndvylvthlmgadlnnivkcqkltddhvqf
liyqilrglkyihsadiihrdlkpsnlavnedcelkildfglarhtddemtgyvatrwyr
apeimlnwmhynqtvdiwsvgcimaelltgrtlfpgtdhidqlklilrlvgtpgaellkk
issesarnyiqslaqmpkmnfanvfiganplavdllekmlvldsdkritaaqalahayfa
qyhdpddepvadpydqsfesrdllidewksltydevisfvpppl

Timeline for d5nzzg_:

• d5nzzg_ first appeared in SCOPe 2.07