SCOPe 2.08: Domain d5nxae_: 5nxa E:

Lineage for d5nxae_ (5nxa E:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.127: L-aspartase-like [48556] (1 superfamily)
   multihelical, consists of three all-alpha domains

4. Superfamily a.127.1: L-aspartase-like [48557] (3 families)

5. Family a.127.1.0: automated matches [191431] (1 protein)
   not a true family

6. Protein automated matches [190621] (30 species)
   not a true protein

7. Species Homo sapiens [TaxId:63221] [352880] (3 PDB entries)

8. Domain d5nxae_: 5nxa E: [352993]
   automated match to d2j91b_
   complexed with amz, cl, fum, sss

Details for d5nxae_

PDB Entry: 5nxa, 2.4 Å

PDB Description: crystal structure of neanderthal adenylosuccinate lyase (adsl)in complex with its products aicar and fumarate

PDB Compounds: (E:) adenylosuccinate lyase

SCOPe Domain Sequences for d5nxae_:

Sequence, based on SEQRES records:

>d5nxae_ a.127.1.0 (E:) automated matches {Homo sapiens [TaxId: 63221]}
gspdsyrsplasryaspemcfvfsdrykfrtwrqlwlwlaeaeqtlglpitdeqiqemks
nlenidfkmaaeeekrlrhdvmahvhtfghccpkaagiihlgatscyvgdntdliilrna
ldlllpklarvisrladfakeraslptlgfthfqpaqlttvgkrcclwiqdlcmdlqnlk
rvrddlrfrgvkgttgtqasflqlfegddhkveqldkmvtekagfkrafiitgqtytrkv
dievlsvlaslgasvhkictdirllanlkemeepfekqqigssampykrnpmrserccsl
arhlmtlvmdplqtasvqwfertlddsanrriclaeafltadtilntlqniseglvvypk
vierrirqelpfmateniimamvkaggsrqdchekirvlsqqaasvvkqeggdndlieri
qadayfspihsqldhlldpssftgrasqqvqrfleeevypllkpyesvmkvkaelcl

Sequence, based on observed residues (ATOM records):

>d5nxae_ a.127.1.0 (E:) automated matches {Homo sapiens [TaxId: 63221]}
gspdsyrsplasryaspemcfvfsdrykfrtwrqlwlwlaeaeqtlglpitdeqiqemks
nlenidfkmaaeeekrlrhdvmahvhtfghccpkaagiihlgatscyvgdntdliilrna
ldlllpklarvisrladfakeraslptlgfthfqpaqlttvgkrcclwiqdlcmdlqnlk
rvrddlrfrgvkgttgtqasflqlfegddhkveqldkmvtekagfkrafiitgqtytrkv
dievlsvlaslgasvhkictdirllanlkemeepfekqqigssampykrnpmrserccsl
arhlmtlvmdplqtasvqwfertlddsanrriclaeafltadtilntlqniseglvvypk
vierrirqelpfmateniimchekirvlsqqaasvvkqeggdndlieriqadayfspihs
qldhlldpssftgrasqqvqrfleeevypllkpyesvmkvkaelcl

Timeline for d5nxae_:

• d5nxae_ first appeared in SCOPe 2.07