SCOPe 2.08: Domain d5o1sa_: 5o1s A:

Lineage for d5o1sa_ (5o1s A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Mouse (Mus musculus) [TaxId:10090] [194605] (31 PDB entries)

8. Domain d5o1sa_: 5o1s A: [352965]
   automated match to d4nifa_
   complexed with 9hb, na

Details for d5o1sa_

PDB Entry: 5o1s, 1.9 Å

PDB Description: dimethyl fumarate is an allosteric covalent inhibitor of the p90 ribosomal s6 kinases

PDB Compounds: (A:) Ribosomal protein S6 kinase alpha-3

SCOPe Domain Sequences for d5o1sa_:

Sequence, based on SEQRES records:

>d5o1sa_ d.144.1.0 (A:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
siqftdgyevkedigvgsysvckrcihkatnmefavkiidkskrdpteeieillrygqhp
niitlkdvyddgkyvyvvtelmkggelldkilrqkffsereasavlftitktveylhaqg
vvhrdlkpsnilyvdesgnpesiricdfgfakqlraengllmtpcytanfvapevlerqg
ydaacdiwslgvllytmltgytpfangpddtpeeilarigsgkfslsggywnsvsdtakd
lvskmlhvdphqrltaalvlrhpwivhwdqlpqyqlnrqdaphlvkgamaatysalnr

Sequence, based on observed residues (ATOM records):

>d5o1sa_ d.144.1.0 (A:) automated matches {Mouse (Mus musculus) [TaxId: 10090]}
siqftdgyevkedisvckrcihkatnmefavkiidkskrdpteeieillrygqhpniitl
kdvyddgkyvyvvtelmkggelldkilrqkffsereasavlftitktveylhaqgvvhrd
lkpsnilyvdesgnpesiricdfgfakqlraengllmtpcnfvapevlerqgydaacdiw
slgvllytmltgytpfangpddtpeeilarigsgkfslsggywnsvsdtakdlvskmlhv
dphqrltaalvlrhpwivhwdqlpqyqlnrqdaphlvkgamaatysalnr

Timeline for d5o1sa_:

• d5o1sa_ first appeared in SCOPe 2.07