SCOPe 2.08: Domain d6f3ea_: 6f3e A:

Lineage for d6f3ea_ (6f3e A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d6f3ea_: 6f3e A: [352547]
   automated match to d4y73a_
   complexed with cjq, so4

Details for d6f3ea_

PDB Entry: 6f3e, 2.67 Å

PDB Description: irak4 in complex with inhibitor

PDB Compounds: (A:) interleukin-1 receptor-associated kinase 4

SCOPe Domain Sequences for d6f3ea_:

Sequence, based on SEQRES records:

>d6f3ea_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkklaamvditt
eelkqqfdqeikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldgtppl
swhmrckiaqgaanginflhenhhihrdiksanilldeaftakisdfglarasekfaqtv
mtsrivgttaymapealrgeitpksdiysfgvvlleiitglpavdehrepqllldikeei
edeektiedyidkkmndadstsveamysvasqclhekknkrpdikkvqqllqemt

Sequence, based on observed residues (ATOM records):

>d6f3ea_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkkllkqqfdqe
ikvmakcqhenlvellgfslclvyvympngslldrlscldgtpplswhmrckiaqgaang
inflhenhhihrdiksanilldeaftakisdfglatvmtsrivgttaymapealrgeitp
ksdiysfgvvlleiitglpavdehrepqllldikeeiedeektiedyidkkmndadstsv
eamysvasqclhekknkrpdikkvqqllqemt

Timeline for d6f3ea_:

• d6f3ea_ first appeared in SCOPe 2.07