SCOPe 2.08: Domain d5vrne_: 5vrn E:

Lineage for d5vrne_ (5vrn E:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (73 proteins)
   also known as short-chain dehydrogenases and SDR family
   parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
   has additional subdomain(s) that are not in the common domain
   

6. Protein Enoyl-ACP reductase [51791] (11 species)

7. Species Mycobacterium tuberculosis, TB, gene InhA [TaxId:1773] [51793] (96 PDB entries)

8. Domain d5vrne_: 5vrn E: [352258]
   automated match to d4tzka_
   complexed with 9jm

Details for d5vrne_

PDB Entry: 5vrn, 2.55 Å

PDB Description: crystal structure of the inha from mycobacterium tuberculosis in complex with an12855, ebsi 4333.

PDB Compounds: (E:) Enoyl-[acyl-carrier-protein] reductase [NADH]

SCOPe Domain Sequences for d5vrne_:

Sequence; same for both SEQRES and ATOM records:

>d5vrne_ c.2.1.2 (E:) Enoyl-ACP reductase {Mycobacterium tuberculosis, TB, gene InhA [TaxId: 1773]}
tglldgkrilvsgiitdssiafhiarvaqeqgaqlvltgfdrlrliqritdrlpakapll
eldvqneehlaslagrvteaigagnkldgvvhsigfmpqtgmginpffdapyadvskgih
isaysyasmakallpimnpggsivgmdfdpsrampaynwmtvaksalesvnrfvareagk
ygvrsnlvaagpirtlamsaivggalgeeagaqiqlleegwdqrapigwnmkdatpvakt
vcallsdwlpattgdiiyadggahtqll

Timeline for d5vrne_:

• d5vrne_ first appeared in SCOPe 2.07