Lineage for d5xsub1 (5xsu B:1-135)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2321349Fold a.41: Domain of poly(ADP-ribose) polymerase [47586] (1 superfamily)
    core: 4 helices: bundle; unusual topology
  4. 2321350Superfamily a.41.1: Domain of poly(ADP-ribose) polymerase [47587] (2 families) (S)
    duplication: consists of 2 helix-loop-helix structural repeats
    automatically mapped to Pfam PF02877
  5. 2321375Family a.41.1.0: automated matches [227223] (1 protein)
    not a true family
  6. 2321376Protein automated matches [226964] (2 species)
    not a true protein
  7. 2321377Species Human (Homo sapiens) [TaxId:9606] [225405] (47 PDB entries)
  8. 3051507Domain d5xsub1: 5xsu B:1-135 [351569]
    Other proteins in same PDB: d5xsua2, d5xsub2, d5xsuc2, d5xsud2
    automated match to d4hhyd1
    complexed with 8e3, so4

Details for d5xsub1

PDB Entry: 5xsu (more details), 2.4 Å

PDB Description: novel orally efficacious inhibitors complexed with parp1
PDB Compounds: (B:) Poly [ADP-ribose] polymerase 1

SCOPe Domain Sequences for d5xsub1:

Sequence, based on SEQRES records: (download)

>d5xsub1 a.41.1.0 (B:1-135) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ksklpkpvqdlikmifdvesmkkamveyeidlqkmplgklskrqiqaaysilsevqqavs
qgssdsqildlsnrfytliphdfgmkkppllnnadsvqakaemldnlldievaysllrgg
sddsskdpidvnyek

Sequence, based on observed residues (ATOM records): (download)

>d5xsub1 a.41.1.0 (B:1-135) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ksklpkpvqdlikmifdvesmkkamveyeidlqkmplgklskrqiqaaysilsevqqaqg
ssdsqildlsnrfytliphdfkkppllnnadsvqakaemldnlldievaysllrggkdpi
dvnyek

SCOPe Domain Coordinates for d5xsub1:

Click to download the PDB-style file with coordinates for d5xsub1.
(The format of our PDB-style files is described here.)

Timeline for d5xsub1:

  • d5xsub1 appears in periodic updates to SCOPe 2.07 starting on 2018-04-26