Lineage for d6bw2b_ (6bw2 B:)

  1. Root: SCOPe 2.08
  2. 3021034Class f: Membrane and cell surface proteins and peptides [56835] (69 folds)
  3. 3021035Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
    multi-helical domains of various folds which is thought to unfold in the membrane
  4. 3021129Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families) (S)
    PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain
  5. 3021130Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
    Pfam PF00452
  6. 3021303Protein EAT/MCL-1 (Myeloid cell leukemia sequence 1) [118212] (2 species)
  7. 3021304Species Human (Homo sapiens) [TaxId:9606] [188549] (62 PDB entries)
  8. 3021436Domain d6bw2b_: 6bw2 B: [349801]
    automated match to d2kbwa_
    complexed with ecy

Details for d6bw2b_

PDB Entry: 6bw2 (more details), 2.75 Å

PDB Description: mcl-1 complexed with small molecules
PDB Compounds: (B:) Induced myeloid leukemia cell differentiation protein Mcl-1

SCOPe Domain Sequences for d6bw2b_:

Sequence; same for both SEQRES and ATOM records: (download)

>d6bw2b_ f.1.4.1 (B:) EAT/MCL-1 (Myeloid cell leukemia sequence 1) {Human (Homo sapiens) [TaxId: 9606]}
elyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafqgml
rkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqescieplae
sitdvlvrtkrdwlvkqrgwdgfveffh

SCOPe Domain Coordinates for d6bw2b_:

Click to download the PDB-style file with coordinates for d6bw2b_.
(The format of our PDB-style files is described here.)

Timeline for d6bw2b_: