SCOPe 2.08: Domain d6b3ga_: 6b3g A:

Lineage for d6b3ga_ (6b3g A:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.50: Acid proteases [50629] (1 superfamily)
   barrel, closed; n=6, S=10, complex topology

4. Superfamily b.50.1: Acid proteases [50630] (4 families)

5. Family b.50.1.1: Retroviral protease (retropepsin) [50631] (9 proteins)
   dimer of identical mono-domain chains, each containing (6,10) barrel

6. Protein Human immunodeficiency virus type 1 protease [50632] (9 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [50633] (590 PDB entries)
   Uniprot P35963 57-155 ! Uniprot P04587 69-167 ! Uniprot P03366 69-167 ! Uniprot P03367 69-167 ! Uniprot P03368 69-167

8. Domain d6b3ga_: 6b3g A: [349600]
   automated match to d1mrwa_
   complexed with cky, cl

Details for d6b3ga_

PDB Entry: 6b3g, 1.5 Å

PDB Description: crystal structure of hiv protease complexed with n-(3-fluoro-2-(2- ((2s,6s)-6-methyl-1-(phenylsulfonyl)piperazin-2-yl)ethyl)phenyl)-3,3- bis(4-fluorophenyl)propanamide

PDB Compounds: (A:) hiv-1 protease

SCOPe Domain Sequences for d6b3ga_:

Sequence; same for both SEQRES and ATOM records:

>d6b3ga_ b.50.1.1 (A:) Human immunodeficiency virus type 1 protease {Human immunodeficiency virus type 1 [TaxId: 11676]}
pqitlwkrplvtikiggqlkealldtgaddtvieemslpgrwkpkmiggiggfikvrqyd
qiiieicghkaigtvlvgptpvniigrnlltqigctlnf

Timeline for d6b3ga_:

• d6b3ga_ first appeared in SCOPe 2.07