Lineage for d1d8ra_ (1d8r A:)

  1. Root: SCOP 1.65
  2. 305035Class c: Alpha and beta proteins (a/b) [51349] (121 folds)
  3. 320020Fold c.71: Dihydrofolate reductases [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 320021Superfamily c.71.1: Dihydrofolate reductases [53597] (1 family) (S)
  5. 320022Family c.71.1.1: Dihydrofolate reductases [53598] (3 proteins)
  6. 320113Protein Dihydrofolate reductases, eukaryotic type [53605] (4 species)
  7. 320123Species Fungus (Pneumocystis carinii) [TaxId:4754] [53608] (11 PDB entries)
  8. 320130Domain d1d8ra_: 1d8r A: [34920]
    complexed with ndp, tab

Details for d1d8ra_

PDB Entry: 1d8r (more details), 2.1 Å

PDB Description: structural studies on bio-active compounds. crystal structure and molecular modeling studies on the pneumocystis carinii dihydrofolate reductase cofactor complex with tab, a highly selective antifolate.

SCOP Domain Sequences for d1d8ra_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1d8ra_ c.71.1.1 (A:) Dihydrofolate reductases, eukaryotic type {Fungus (Pneumocystis carinii)}

SCOP Domain Coordinates for d1d8ra_:

Click to download the PDB-style file with coordinates for d1d8ra_.
(The format of our PDB-style files is described here.)

Timeline for d1d8ra_: