SCOPe 2.08: Domain d5mk8a2: 5mk8 A:1072-1288

Lineage for d5mk8a2 (5mk8 A:1072-1288)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.42: beta-Trefoil [50352] (8 superfamilies)
   barrel, closed; n=6, S=12; and a hairpin triplet; meander
   duplication: has internal pseudo threefold symmetry

4. Superfamily b.42.4: STI-like [50386] (3 families)

5. Family b.42.4.2: Clostridium neurotoxins, C-terminal domain [50399] (3 proteins)
   overall fold is very similar to that of the STI family
   automatically mapped to Pfam PF07951

6. Protein automated matches [229100] (6 species)
   not a true protein

7. Species Clostridium botulinum [TaxId:1491] [229101] (14 PDB entries)

8. Domain d5mk8a2: 5mk8 A:1072-1288 [346935]
   Other proteins in same PDB: d5mk8a1, d5mk8b1
   automated match to d5v38a2
   complexed with cl, fmt

Details for d5mk8a2

PDB Entry: 5mk8, 1.95 Å

PDB Description: crystal structure of the receptor-binding domain of the fa hybrid clostridium botulinum neurotoxin

PDB Compounds: (A:) Botulinum neurotoxin FA binding domain

SCOPe Domain Sequences for d5mk8a2:

Sequence, based on SEQRES records:

>d5mk8a2 b.42.4.2 (A:1072-1288) automated matches {Clostridium botulinum [TaxId: 1491]}
nkkeikdlydnqsnsgilkdfwgdylqydkpyymlnlydpnkyldvnnvgirgymylkgp
rgrivttniylnstlymgtkfiikkyasgnkdnivrnndrvyinvvvknkeyrlatnasq
agvekilsaveipdvgnlsqvvvmksendqgirnkckmnlqdnngndigfigfhqfnnia
klvasnwynrqigkasrtfgcswefipvddgwgessl

Sequence, based on observed residues (ATOM records):

>d5mk8a2 b.42.4.2 (A:1072-1288) automated matches {Clostridium botulinum [TaxId: 1491]}
nkkeikdlydnqsnsgilkdfwgdylqydkpyymlnlydpnkyldvnnvgirgymylkgp
rgrivttniylnstlymgtkfiikkyasgnkdnivrnndrvyinvvvknkeyrlatnasq
agvekilsaveipdvgnlsqvvvmksenkckmnlqdnngndigfigfhqfnniaklvasn
wynrqigkasrtfgcswefipvddgwgessl

Timeline for d5mk8a2:

• d5mk8a2 first appeared in SCOPe 2.07