SCOPe 2.08: Domain d2dfpa_: 2dfp A:

Lineage for d2dfpa_ (2dfp A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (43 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.1: Acetylcholinesterase-like [53475] (6 proteins)
   automatically mapped to Pfam PF00135

6. Protein Acetylcholinesterase [53476] (6 species)

7. Species Pacific electric ray (Torpedo californica) [TaxId:7787] [53477] (98 PDB entries)
   Uniprot P04058 25-556

8. Domain d2dfpa_: 2dfp A: [34597]
   complexed with mes, nag

Details for d2dfpa_

PDB Entry: 2dfp, 2.3 Å

PDB Description: x-ray structure of aged di-isopropyl-phosphoro-fluoridate (dfp) bound to acetylcholinesterase

PDB Compounds: (A:) protein (acetylcholinesterase)

SCOPe Domain Sequences for d2dfpa_:

Sequence; same for both SEQRES and ATOM records:

>d2dfpa_ c.69.1.1 (A:) Acetylcholinesterase {Pacific electric ray (Torpedo californica) [TaxId: 7787]}
dhsellvntksgkvmgtrvpvlsshisaflgipfaeppvgnmrfrrpepkkpwsgvwnas
typnncqqyvdeqfpgfsgsemwnpnremsedclylniwvpsprpksttvmvwiygggfy
sgsstldvyngkylayteevvlvslsyrvgafgflalhgsqeapgnvglldqrmalqwvh
dniqffggdpktvtifgesaggasvgmhilspgsrdlfrrailqsgspncpwasvsvaeg
rrravelgrnlncnlnsdeelihclrekkpqelidvewnvlpfdsifrfsfvpvidgeff
ptslesmlnsgnfkktqillgvnkdegsffllygapgfskdseskisredfmsgvklsvp
handlgldavtlqytdwmddnngiknrdglddivgdhnvicplmhfvnkytkfgngtyly
ffnhrasnlvwpewmgvihgyeiefvfglplvkelnytaeeealsrrimhywatfaktgn
pnephsqeskwplfttkeqkfidlntepmkvhqrlrvqmcvfwnqflpkllnat

Timeline for d2dfpa_:

• d2dfpa_ first appeared (with stable ids) in SCOP 1.55
  
• d2dfpa_ appears in SCOPe 2.07