SCOPe 2.08: Domain d5ajra2: 5ajr A:29-31

Lineage for d5ajra2 (5ajr A:29-31)

1. Root: SCOPe 2.08

2. Class l: Artifacts [310555] (1 fold)

3. Fold l.1: Tags [310573] (1 superfamily)

4. Superfamily l.1.1: Tags [310607] (1 family)

5. Family l.1.1.1: Tags [310682] (2 proteins)

6. Protein N-terminal Tags [310894] (1 species)

7. Species Synthetic [311501] (15360 PDB entries)

8. Domain d5ajra2: 5ajr A:29-31 [345533]
   Other proteins in same PDB: d5ajra1
   complexed with hem, vt1

Details for d5ajra2

PDB Entry: 5ajr, 2.75 Å

PDB Description: sterol 14-alpha demethylase (cyp51) from trypanosoma cruzi in complex with the 1-tetrazole derivative vt-1161 ((r)-2-( 2,4-difluorophenyl)-1,1-difluoro-3-(1h-tetrazol-1-yl)-1-(5- (4-(2,2,2-trifluoroethoxy)phenyl)pyridin-2-yl)propan-2-ol)

PDB Compounds: (A:) Sterol 14-alpha demethylase

SCOPe Domain Sequences for d5ajra2:

Sequence; same for both SEQRES and ATOM records:

>d5ajra2 l.1.1.1 (A:29-31) N-terminal Tags {Synthetic}
kkt

Timeline for d5ajra2:

• d5ajra2 first appeared in SCOPe 2.07