SCOPe 2.08: Domain d4i50f3: 4i50 F:77-378

Lineage for d4i50f3 (4i50 F:77-378)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.142: ATP-grasp [56058] (2 superfamilies)
   Consists of two subdomains with different alpha+beta folds
   shares functional and structural similarities with the PIPK and protein kinase superfamilies

4. Superfamily d.142.1: Glutathione synthetase ATP-binding domain-like [56059] (11 families)

5. Family d.142.1.10: Tubulin tyrosine ligase (TTL) C-terminal domain-like [310626] (2 proteins)
   Pfam PF03133; PubMed 22020298

6. Protein Tubulin tyrosine ligase (TTL) C-terminal domain [310728] (3 species)

7. Species Chicken (Gallus gallus) [TaxId:9031] [311385] (176 PDB entries)

8. Domain d4i50f3: 4i50 F:77-378 [343958]
   Other proteins in same PDB: d4i50a1, d4i50a2, d4i50b1, d4i50b2, d4i50c1, d4i50c2, d4i50d1, d4i50d2, d4i50e_, d4i50f1, d4i50f2
   complexed with acp, ca, cl, ep, gdp, gol, gtp, mes, mg

Details for d4i50f3

PDB Entry: 4i50, 2.3 Å

PDB Description: crystal structure of tubulin-stathmin-ttl-epothilone a complex

PDB Compounds: (F:) Tubulin Tyrosine ligase, TTL

SCOPe Domain Sequences for d4i50f3:

Sequence, based on SEQRES records:

>d4i50f3 d.142.1.10 (F:77-378) Tubulin tyrosine ligase (TTL) C-terminal domain {Chicken (Gallus gallus) [TaxId: 9031]}
lvkliktspelsesctwfpesyviyptnlktpvapaqngirhlinntrtderevflaayn
rrregregnvwiakssagakgegilisseaselldfideqgqvhviqkylekplllepgh
rkfdirswvlvdhlyniylyregvlrtssepynsanfqdktchltnhciqkeysknygry
eegnemffeefnqylmdalnttlensillqikhiirsclmciepaistkhlhyqsfqlfg
fdfmvdeelkvwlievngapacaqklyaelcqgivdvaissvfpladtgqktsqptsifi
kl

Sequence, based on observed residues (ATOM records):

>d4i50f3 d.142.1.10 (F:77-378) Tubulin tyrosine ligase (TTL) C-terminal domain {Chicken (Gallus gallus) [TaxId: 9031]}
lvkliktspelsesctwfpesylaaynrrregregnvwiaksisseaselldfidevhvi
qkylekplllepghrkfdirswvlvdhlyniylyregvlrtstnhciqkeyeegnemffe
efnqylmdalnttlensillqikhiirsclmciepaistkhlhyqsfqlfgfdfmvdeel
kvwlievngapacaqklyaelcqgivdvaissvfpladptsifikl

Timeline for d4i50f3:

• d4i50f3 first appeared in SCOPe 2.07