SCOPe 2.08: Domain d4c2mp_: 4c2m P:

Lineage for d4c2mp_ (4c2m P:)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.29: beta and beta-prime subunits of DNA dependent RNA-polymerase [64483] (1 superfamily)
   Multidomain subunits of complex domain organization

4. Superfamily e.29.1: beta and beta-prime subunits of DNA dependent RNA-polymerase [64484] (3 families)
   The catalytic site is formed by the association of two double-psi beta-barrel domains, one from each subunit

5. Family e.29.1.2: RNA-polymerase beta-prime [64490] (4 proteins)

6. Protein RNA polymerase I subunit A190 [346118] (1 species)

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [346415] (2 PDB entries)

8. Domain d4c2mp_: 4c2m P: [343928]
   Other proteins in same PDB: d4c2m1_, d4c2m2_, d4c2m3_, d4c2mb_, d4c2mc1, d4c2mc2, d4c2me1, d4c2me2, d4c2mf_, d4c2mg1, d4c2mh_, d4c2mi1, d4c2mi2, d4c2mj_, d4c2mk_, d4c2ml_, d4c2mm_, d4c2mn_, d4c2mq_, d4c2mr1, d4c2mr2, d4c2mt1, d4c2mt2, d4c2mu_, d4c2mv1, d4c2mw_, d4c2mx1, d4c2mx2, d4c2my_, d4c2mz_
   automated match to d4c3ha_
   complexed with so4, zn

Details for d4c2mp_

PDB Entry: 4c2m, 2.8 Å

PDB Description: structure of rna polymerase i at 2.8 a resolution

PDB Compounds: (P:) DNA-directed RNA polymerase I subunit rpa190

SCOPe Domain Sequences for d4c2mp_:

Sequence, based on SEQRES records:

>d4c2mp_ e.29.1.2 (P:) RNA polymerase I subunit A190 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
mdiskpvgseitsvdfgiltakeirnlsakqitnptvldnlghpvsgglydlalgaflrn
lcstcgldekfcpghqghielpvpcynplffnqlyiylrasclfchhfrlksvevhryac
klrllqyglidesykldeitlgslnssmytddeaiednedemdgegskqskdisstllne
lkskrseyvdmaiakalsdgrttergsftatvnderkklvhefhkkllsrgkcdncgmfs
pkfrkdgftkifetalnekqitnnrvkgfirqdmikkqkqakkldgsneasandeesfdv
grnpttrpktgstyilstevknildtvfrkeqcvlqyvfhsrpnlsrklvkadsffmdvl
vvpptrfrlpsklgeevhensqnqllskvlttsllirdlnddlsklqkdkvsledrrvif
srlmnafvtiqndvnafidstkaqgrtsgkvpipgvkqalekkeglfrkhmmgkrvnyaa
rsvispdpnietneigvppvfavkltypepvtayniaelrqavingpdkwpgatqiqned
gslvsligmsveqrkalanqlltpssnvsthtlnkkvyrhiknrdvvlmnrqptlhkasm
mghkvrvlpnektlrlhyantgaynadfdgdemnmhfpqnenaraealnlantdsqyltp
tsgspvrgliqdhisagvwltskdsfftreqyqqyiygcirpedghttrskivtlpptif
kpyplwtgkqiittvllnvtppdmpginlisknkikneywgkgslenevlfkdgallcgi
ldksqygaskygivhslhevygpevaakvlsvlgrlftnyitataftcgmddlrltaegn
kwrtdilktsvdtgreaaaevtnldkdtpaddpellkrlqeilrdnnksgildavtsskv
naitsqvvskcvpdgtmkkfpcnsmqamalsgakgsnvnvsqimcllgqqalegrrvpvm
vsgktlpsfkpyetdamaggyvkgrfysgikpqeyyfhcmagreglidtavktsrsgylq
rcltkqlegvhvsydnsirdadgtlvqfmyggdaiditkeshmtqfefcldnyyallkky
npsaliehldvesalkyskktlkyrkkhskephykqsvkydpvlakynpakylgsvsenf
qdklesfldknsklfkssdgvnekkfralmqlkymrslinpgeavgiiasqsvgepstqm
tlntfhfaghgaanvtlgiprlreivmtasaaiktpqmtlpiwndvsdeqadtfcksisk
vllsevidkvivtettgtsntaggnaarsyvihmrffdnneyseeydvskeelqnvisnq
fihlleaaivkeikkqkrttgpdigvavprlqtdvansssnskrleedndeeqshkktkq
avsydepdedeietmreaekssdeegidsdkesdsdsededvdmneqinksiveannnmn
kvqrdrqsaiishhrfitkynfddesgkwcefklelaadtekllmvniveeicrksiirq
iphidrcvhpepengkrvlvtegvnfqamwdqeafidvdgitsndvaavlktygveaarn
tivneinnvfsryaisvsfrhldliadmmtrqgtylafnrqgmetstssfmkmsyettcq
fltkavldnereqldspsarivvgklnnvgtgsfdvlakvpnaa

Sequence, based on observed residues (ATOM records):

>d4c2mp_ e.29.1.2 (P:) RNA polymerase I subunit A190 {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
mdiskpvgseitsvdfgiltakeirnlsakqitnptvldnlghpvsgglydlalgaflrn
lcstcgldekfcpghqghielpvpcynplffnqlyiylrasclfchhfrlksvevhryac
klrllqyglidesykldeitlsstllnelkskrseyvdmaiakalsdgrttergsftatv
nderkklvhefhkkllsrgkcdncgmfspkfrkdgftkifetalnekqitnnrvkgfirq
dstyilstevknildtvfrkeqcvlqyvfhsrpnlsrklvkadsffmdvlvvpptrfrlp
sklgeevhensqnqllskvlttsllirdlnddlsklqkdkvsledrrvifsrlmnafvti
qndvnafidstkaqgrtsgkvpipgvkqalekkeglfrkhmmgkrvnyaarsvispdpni
etneigvppvfavkltypepvtayniaelrqavingpdkwpgatqiqnedgslvsligms
veqrkalanqlltpssnvsthtlnkkvyrhiknrdvvlmnrqptlhkasmmghkvrvlpn
ektlrlhyantgaynadfdgdemnmhfpqnenaraealnlantdsqyltptsgspvrgli
qdhisagvwltskdsfftreqyqqyiygcirpedghttrskivtlpptifkpyplwtgkq
iittvllnvtppdmpginlisknkikneywgkgslenevlfkdgallcgildksqygask
ygivhslhevygpevaakvlsvlgrlftnyitataftcgmddlrltaegnkwrtdilkts
vdtgreaaaevtnldkdtpaddpellkrlqeilrdnnksgildavtsskvnaitsqvvsk
cvpdgtmkkfpcnsmqamalsgakgsnvnvsqimcllgqqalegrrvpvmvsgktlpsfk
pyetdamaggyvkgrfysgikpqeyyfhcmagreglidtavktsrsgylqrcltkqlegv
hvsydnsirdadgtlvqfmyggdaiditkeshmtqfefcldnyyallkkynpsaliehld
vesalkyskktlkyrkkhskephykqsvkydpvlakynpakylgsvsenfqdklesfldk
nsklfkssdgvnekkfralmqlkymrslinpgeavgiiasqsvgepstqmtlntfnvtlg
iprlreivmtasaaiktpqmtlpiwndvsdeqadtfcksiskvllsevidkvivtettaa
rsyvihmrffdnneyseeydvskeelqnvisnqfihlleaaivkeikkqkdigvavprns
krleedndeeqshkktkqavsydepdedeietmnkvqrdrqsaiishhrfitkynfddes
gkwcefklelaadtekllmvniveeicrksiirqiphidrcvhpepengkrvlvtegvnf
qamwdqeafidvdgitsndvaavlktygveaarntivneinnvfsryaisvsfrhldlia
dmmtrqgtylafnrqgmetstssfmkmsyettcqfltkavldnereqldspsarivvgkl
nnvgtgsfdvlakvpnaa

Timeline for d4c2mp_:

• d4c2mp_ first appeared in SCOPe 2.07