SCOPe 2.06: Domain d5xhgd1: 5xhg D:1-120

Lineage for d5xhgd1 (5xhg D:1-120)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.1: V set domains (antibody variable domain-like) [48727] (33 proteins)

6. Protein Immunoglobulin heavy chain variable domain, VH [88543] (22 species)
   VH domains of human and mouse antibodies are clustered by the sequence similarity within the germline encoded segment and then by the size of the complementarity determining regions CDR1 and CDR2, so the clusters may correspond to putative germline families in the species genomes; VH domains with artificial or grafted exogenous CDRs are listed as engineered species

7. Species Escherichia coli [TaxId:316407] [343346] (1 PDB entry)

8. Domain d5xhgd1: 5xhg D:1-120 [343347]
   Other proteins in same PDB: d5xhga1, d5xhga2, d5xhgb2, d5xhgc1, d5xhgc2, d5xhgd2
   automated match to d1n8zb1
   complexed with edo, oaz, peg, so4

Details for d5xhgd1

PDB Entry: 5xhg, 1.76 Å

PDB Description: crystal structure of trastuzumab fab fragment bearing ne-(o- azidobenzyloxycarbonyl)-l-lysine

PDB Compounds: (D:) polypeptide(H)

SCOPe Domain Sequences for d5xhgd1:

Sequence; same for both SEQRES and ATOM records:

>d5xhgd1 b.1.1.1 (D:1-120) Immunoglobulin heavy chain variable domain, VH {Escherichia coli [TaxId: 316407]}
evqlvesggglvqpggslrlscaasgfnikdtyihwvrqapgkglewvariyptngytry
adsvkgrftisadtskntaylqmnslraedtavyycsrwggdgfyamdywgqgtlvtvss

Timeline for d5xhgd1:

• d5xhgd1 is new in SCOPe 2.06-stable
  
• d5xhgd1 appears in SCOPe 2.07
  
• d5xhgd1 appears in the current release, SCOPe 2.08