Lineage for d5y2tb1 (5y2t B:207-475)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2011944Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
    multihelical; 3 layers or orthogonally packed helices
  4. 2011945Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families) (S)
  5. 2011946Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 protein domains)
  6. 2012438Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)
  7. 2012439Species Human (Homo sapiens) [TaxId:9606] [48525] (113 PDB entries)
    Uniprot P37231 232-505
  8. 2012464Domain d5y2tb1: 5y2t B:207-475 [343302]
    Other proteins in same PDB: d5y2tb2
    automated match to d2xkwa_
    complexed with 8lx

Details for d5y2tb1

PDB Entry: 5y2t (more details), 1.7 Å

PDB Description: structure of ppargamma ligand binding domain - lobeglitazone complex
PDB Compounds: (B:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d5y2tb1:

Sequence, based on SEQRES records: (download)

>d5y2tb1 a.123.1.1 (B:207-475) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiykd

Sequence, based on observed residues (ATOM records): (download)

>d5y2tb1 a.123.1.1 (B:207-475) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgspfviydmnslmmgedkikfkhitkev
airifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkd
gvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdr
pgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvik
ktetdmslhpllqeiykd

SCOPe Domain Coordinates for d5y2tb1:

Click to download the PDB-style file with coordinates for d5y2tb1.
(The format of our PDB-style files is described here.)

Timeline for d5y2tb1:

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Domains from same chain:
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d5y2tb2
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Domains from other chains:
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d5y2ta_