Lineage for d6brub_ (6bru B:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2195565Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2195566Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2199100Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2199101Protein automated matches [190417] (25 species)
    not a true protein
  7. 2199241Species Human (Homo sapiens) [TaxId:9606] [187294] (882 PDB entries)
  8. 2299637Domain d6brub_: 6bru B: [342938]
    automated match to d3op5a_
    complexed with e5m, edo, so4

Details for d6brub_

PDB Entry: 6bru (more details), 1.8 Å

PDB Description: crystal structure of the human vaccinia-related kinase bound to a (s)- 2-phenylaminopteridinone inhibitor
PDB Compounds: (B:) Serine/threonine-protein kinase VRK1

SCOPe Domain Sequences for d6brub_:

Sequence, based on SEQRES records: (download)

>d6brub_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
favgeiitdmaaaawkvglpigqggfgciyladmnssesvgsdapcvvkvepsdngplft
elkfyqraakpeqiqkwirtrklkylgvpkywgsglhdkngksyrfmimdrfgsdlqkiy
eanakrfsrktvlqlslrildileyiheheyvhgdikasnlllnyknpdqvylvdyglay
rycpegvhkayaadpkrchdgtieftsidahngvapsrrgdleilgycmiqwltghlpwe
dnlkdpkyvrdskiryreniaslmdkcfpaanapgeiakymetvklldytekplyenlrd
illqglkaigskddgkldl

Sequence, based on observed residues (ATOM records): (download)

>d6brub_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
favgeiitdmaaaawkvglpiciyladmnssdapcvvkvepgplftelkfyqraakpeqi
qkwirtrklkylgvpkywgsglhdkyrfmimdrfgsdlqkiyeanakrfsrktvlqlslr
ildileyiheheyvhgdikasnlllnyknpdqvylvdyglayrycpegvhkayaadpkrc
hdgtieftsidahngvapsrrgdleilgycmiqwltghlpwednlkdpkyvrdskiryre
niaslmdkcfpaanapgeiakymetvklldytekplyenlrdillqglkaigskddgkld
l

SCOPe Domain Coordinates for d6brub_:

Click to download the PDB-style file with coordinates for d6brub_.
(The format of our PDB-style files is described here.)

Timeline for d6brub_:

  • d6brub_ appears in periodic updates to SCOPe 2.06 starting on 2017-12-14