Lineage for d5j8mb_ (5j8m B:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2537076Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
    8-stranded mixed beta-sheet; 2 layers: alpha/beta
  4. 2537077Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (5 families) (S)
  5. 2537078Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain [55875] (2 proteins)
  6. 2537079Protein HSP90 [55876] (3 species)
  7. 2537164Species Human (Homo sapiens) [TaxId:9606] [55878] (144 PDB entries)
    Uniprot P08238 10-220 # HSP 90-beta isoform ! Uniprot P07900 16-223
  8. 2537282Domain d5j8mb_: 5j8m B: [342267]
    automated match to d2xjxa_
    complexed with 6dl; mutant

Details for d5j8mb_

PDB Entry: 5j8m (more details), 1.9 Å

PDB Description: crystal structure of hsp90-alpha n-domain l107a mutant in complex with 5-(5-bromo-2,4-dihydroxy-phenyl)-4-(2-fluoro-phenyl)-2,4-dihydro-[1, 2,4]triazol-3-one
PDB Compounds: (B:) Heat shock protein HSP 90-alpha

SCOPe Domain Sequences for d5j8mb_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5j8mb_ d.122.1.1 (B:) HSP90 {Human (Homo sapiens) [TaxId: 9606]}
evetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskldsgke
lhinlipnkqdrtltivdtgigmtkadlinnagtiaksgtkafmealqagadismigqfg
vgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhlkedqt
eyleerrikeivkkhsqfigypitlfvek

SCOPe Domain Coordinates for d5j8mb_:

Click to download the PDB-style file with coordinates for d5j8mb_.
(The format of our PDB-style files is described here.)

Timeline for d5j8mb_: