Lineage for d5toba_ (5tob A:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2195565Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2195566Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2195690Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 protein domains)
    members organized in the groups and subfamiles specified by the comments
  6. 2198144Protein automated matches [190091] (16 species)
    not a true protein
  7. 2198237Species Human (Homo sapiens) [TaxId:9606] [188447] (653 PDB entries)
  8. 2298885Domain d5toba_: 5tob A: [342186]
    automated match to d3cc6a_
    complexed with yam

Details for d5toba_

PDB Entry: 5tob (more details), 2.12 Å

PDB Description: selectivity switch between fak and pyk2: macrocyclization of fak inhibitors improves pyk2 potency
PDB Compounds: (A:) Protein-tyrosine kinase 2-beta

SCOPe Domain Sequences for d5toba_:

Sequence, based on SEQRES records: (download)

>d5toba_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
iaredvvlnrilgegffgevyegvytnhkgekinvavktckkdctldnkekfmseavimk
nldhphivkligiieeeptwiimelypygelghylernknslkvltlvlyslqickamay
lesincvhrdiavrnilvaspecvklgdfglsryiededyykasvtrlpikwmspesinf
rrfttasdvwmfavcmweilsfgkqpffwlenkdvigvlekgdrlpkpdlcppvlytlmt
rcwdydpsdrprftelvcslsdvyqmekdia

Sequence, based on observed residues (ATOM records): (download)

>d5toba_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
iaredvvlnrilgegffgevyegvythkgekinvavktckdnkekfmseavimknldhph
ivkligiieptwiimelypygelghylernknslkvltlvlyslqickamaylesincvh
rdiavrnilvaspecvklgdfgpikwmspesinfrrfttasdvwmfavcmweilsfgkqp
ffwlenkdvigvlekgdrlpkpdlcppvlytlmtrcwdydpsdrprftelvcslsdvyqm
ekdia

SCOPe Domain Coordinates for d5toba_:

Click to download the PDB-style file with coordinates for d5toba_.
(The format of our PDB-style files is described here.)

Timeline for d5toba_:

  • d5toba_ appears in periodic updates to SCOPe 2.06 starting on 2017-11-30