SCOPe 2.06: Domain d5wr1b_: 5wr1 B:

Lineage for d5wr1b_ (5wr1 B:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (113 PDB entries)
   Uniprot P37231 232-505

8. Domain d5wr1b_: 5wr1 B: [341927]
   automated match to d2xkwa_
   complexed with 8xo

Details for d5wr1b_

PDB Entry: 5wr1, 2.34 Å

PDB Description: covalent bond formation of bifunctional ligand with hpparg-lbd

PDB Compounds: (B:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d5wr1b_:

Sequence, based on SEQRES records:

>d5wr1b_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
tehvqllqvikktetdmslhpllqeiyk

Sequence, based on observed residues (ATOM records):

>d5wr1b_ a.123.1.1 (B:) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
esadlralakhlydsyiksfpltkakarailtgkdkspfviydmnslmmgedkievairi
fqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmnkdgvli
segqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsgdrpgll
nvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqvikktpl
lqeiyk

Timeline for d5wr1b_:

• d5wr1b_ is new in SCOPe 2.06-stable
  
• d5wr1b_ appears in SCOPe 2.07
  
• d5wr1b_ appears in the current release, SCOPe 2.08