SCOPe 2.08: Domain d5pgwb2: 5pgw B:11-23

Lineage for d5pgwb2 (5pgw B:11-23)

1. Root: SCOPe 2.08

2. Class l: Artifacts [310555] (1 fold)

3. Fold l.1: Tags [310573] (1 superfamily)

4. Superfamily l.1.1: Tags [310607] (1 family)

5. Family l.1.1.1: Tags [310682] (2 proteins)

6. Protein N-terminal Tags [310894] (1 species)

7. Species Synthetic [311501] (15360 PDB entries)

8. Domain d5pgwb2: 5pgw B:11-23 [340993]
   Other proteins in same PDB: d5pgwa_, d5pgwb1, d5pgwd1, d5pgwe_
   complexed with 8ka, nap; mutant

Details for d5pgwb2

PDB Entry: 5pgw, 2.37 Å

PDB Description: crystal structure of 11beta-hsd1 double mutant (l262r, f278e) complexed with 2-[(1r,3s,5r,7s)-2-[4-(4-fluorophenyl)phenyl]-6- hydroxyadamantan-2-yl]-1-(3- hydroxyazetidin-1-yl)ethan-1-one

PDB Compounds: (B:) Corticosteroid 11-beta-dehydrogenase isozyme 1

SCOPe Domain Sequences for d5pgwb2:

Sequence; same for both SEQRES and ATOM records:

>d5pgwb2 l.1.1.1 (B:11-23) N-terminal Tags {Synthetic}
asmtggqqmgrgs

Timeline for d5pgwb2:

• d5pgwb2 first appeared in SCOPe 2.06
  
• d5pgwb2 appears in SCOPe 2.07