Lineage for d5w85b_ (5w85 B:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2195565Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2195566Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2199100Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2199101Protein automated matches [190417] (25 species)
    not a true protein
  7. 2199241Species Human (Homo sapiens) [TaxId:9606] [187294] (842 PDB entries)
  8. 2297495Domain d5w85b_: 5w85 B: [340796]
    automated match to d4y73b_
    complexed with 9ys

Details for d5w85b_

PDB Entry: 5w85 (more details), 2.25 Å

PDB Description: crystal structure of irak-4 with a 4,6-diaminonicotinamide inhibitor (compound number 9)
PDB Compounds: (B:) interleukin-1 receptor-associated kinase 4

SCOPe Domain Sequences for d5w85b_:

Sequence, based on SEQRES records: (download)

>d5w85b_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rfhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkklaamvditt
eelkqqfdqeikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldgtppl
swhmrckiaqgaanginflhenhhihrdiksanilldeaftakisdfglarasekfaqtv
mtsrivgttaymapealrgeitpksdiysfgvvlleiitglpavdehrepqllldikeei
edeektiedyidkkmndadstsveamysvasqclhekknkrpdikkvqqllqemta

Sequence, based on observed residues (ATOM records): (download)

>d5w85b_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rfhsfsfyelknvtnnfderpisvggnkmgefgvvykgyvnnttvavkkleelkqqfdqe
ikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldgtpplswhmrckiaq
gaanginflhenhhihrdiksanilldeaftakisdfglarasqtvmtsrivgttaymap
ealrgeitpksdiysfgvvlleiitglpavdehrepqllldikeeiedeektiedyidkk
mndadstsveamysvasqclhekknkrpdikkvqqllqemta

SCOPe Domain Coordinates for d5w85b_:

Click to download the PDB-style file with coordinates for d5w85b_.
(The format of our PDB-style files is described here.)

Timeline for d5w85b_:

  • d5w85b_ appears in periodic updates to SCOPe 2.06 starting on 2017-10-29