Lineage for d5w86d_ (5w86 D:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2195565Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2195566Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2199100Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2199101Protein automated matches [190417] (25 species)
    not a true protein
  7. 2199241Species Human (Homo sapiens) [TaxId:9606] [187294] (842 PDB entries)
  8. 2297426Domain d5w86d_: 5w86 D: [340727]
    automated match to d4hvga_
    complexed with 9yv

Details for d5w86d_

PDB Entry: 5w86 (more details), 2.61 Å

PDB Description: crystal structure of jak3 kinase domain with a 4,6-diaminonicotinamide inhibitor (compound number 7)
PDB Compounds: (D:) Tyrosine-protein kinase JAK3

SCOPe Domain Sequences for d5w86d_:

Sequence, based on SEQRES records: (download)

>d5w86d_ d.144.1.0 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ptifeerhlkyisqlgkgnfgsvelcrydplgdntgalvavkqlqhsgpdqqrdfqreiq
ilkalhsdfivkyrgvsygpgrqslrlvmeylpsgclrdflqrhrarldasrlllyssqi
ckgmeylgsrrcvhrdlaarnilveseahvkiadfglakllpldkdyyvvrepgqspifw
yapeslsdnifsrqsdvwsfgvvlyelftycdkscspsaeflrmmgserdvpalsrllel
leegqrlpappacpaevhelmklcwapspqdrpsfsalgpqldmlw

Sequence, based on observed residues (ATOM records): (download)

>d5w86d_ d.144.1.0 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ptifeerhlkyisqlgkgnfgsvelcrydplgdntgalvavkqlqgpdqqrdfqreiqil
kalhsdfivkyrgvsyslrlvmeylpsgclrdflqrhrarldasrlllyssqickgmeyl
gsrrcvhrdlaarnilveseahvkiadfglakllpldkdyyvvspifwyapeslsdnifs
rqsdvwsfgvvlyelftycdkscspsaeflrmmgserdvpalsrllelleegqrlpappa
cpaevhelmklcwapspqdrpsfsalgpqldmlw

SCOPe Domain Coordinates for d5w86d_:

Click to download the PDB-style file with coordinates for d5w86d_.
(The format of our PDB-style files is described here.)

Timeline for d5w86d_:

  • d5w86d_ appears in periodic updates to SCOPe 2.06 starting on 2017-10-29