Lineage for d5w5oh_ (5w5o H:)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2195565Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2195566Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2199100Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2199101Protein automated matches [190417] (25 species)
    not a true protein
  7. 2199241Species Human (Homo sapiens) [TaxId:9606] [187294] (842 PDB entries)
  8. 2297419Domain d5w5oh_: 5w5o H: [340720]
    automated match to d5ar5b_
    complexed with 9xa

Details for d5w5oh_

PDB Entry: 5w5o (more details), 2.89 Å

PDB Description: identification of potent and selective ripk2 inhibitors for the treatment of inflammatory diseases.
PDB Compounds: (H:) receptor-interacting serine/threonine-protein kinase 2

SCOPe Domain Sequences for d5w5oh_:

Sequence, based on SEQRES records: (download)

>d5w5oh_ d.144.1.0 (H:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
aicsalptipyhkladlrylsrgasgtvssarhadwrvqvavkhlhihtplldserkdvl
reaeilhkarfsyilpilgicnepeflgivteympngslnellhrkteypdvawplrfri
lheialgvnylhnmtppllhhdlktqnilldnefhvkiadfglskwrmmslsqsrssksa
peggtiiymppenyepgqksrasikhdiysyavitwevlsrkqpfedvtnplqimysvsq
ghrpvineeslpydiphrarmisliesgwaqnpderpsflkclielepvlrtfeeitfle
aviqlk

Sequence, based on observed residues (ATOM records): (download)

>d5w5oh_ d.144.1.0 (H:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
aicsalptipyhkladlrylsrgasgtvssarhadwrvqvavkhserkdvlreaeilhka
rfsyilpilgicnepeflgivteympngslnellhrkteypdvawplrfrilheialgvn
ylhnmtppllhhdlktqnilldnefhvkiadfglskwrmgtiiymppenyepikhdiysy
avitwevlsrkqpfedvtnplqimysvsqghrpvineeslpydiphrarmisliesgwaq
npderpsflkclielepvlrtfeeitfleaviqlk

SCOPe Domain Coordinates for d5w5oh_:

Click to download the PDB-style file with coordinates for d5w5oh_.
(The format of our PDB-style files is described here.)

Timeline for d5w5oh_:

  • d5w5oh_ appears in periodic updates to SCOPe 2.06 starting on 2017-10-29