SCOPe 2.08: Domain d5w84a_: 5w84 A:

Lineage for d5w84a_ (5w84 A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d5w84a_: 5w84 A: [340657]
   automated match to d4y73b_
   complexed with 9yy

Details for d5w84a_

PDB Entry: 5w84, 2.9 Å

PDB Description: crystal structure of irak-4 with a 4,6-diaminonicotinamide inhibitor (compound number 4)

PDB Compounds: (A:) interleukin-1 receptor-associated kinase 4

SCOPe Domain Sequences for d5w84a_:

Sequence, based on SEQRES records:

>d5w84a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
fhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkklaamvditte
elkqqfdqeikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldgtppls
whmrckiaqgaanginflhenhhihrdiksanilldeaftakisdfglarasekfaqtvm
tsrivgttaymapealrgeitpksdiysfgvvlleiitglpavdehrepqllldikeeie
deektiedyidkkmndadstsveamysvasqclhekknkrpdikkvqqllqemta

Sequence, based on observed residues (ATOM records):

>d5w84a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
fhsfsfyelknvtnnfderpisvggnkmgeggfgvvykgyvnnttvavkklittkqqfdq
eikvmakcqhenlvellgfssdgddlclvyvympngslldrlscldgtpplswhmrckia
qgaanginflhenhhihrdiksanilldeaftakisdfglarastvmtsrivgttaymap
ealrgeitpksdiysfgvvlleiitglpavdehrepqllldikeeiedeektiedyidkk
mndadstsveamysvasqclhekknkrpdikkvqqllqemta

Timeline for d5w84a_:

• d5w84a_ first appeared in SCOPe 2.06
  
• d5w84a_ appears in SCOPe 2.07