Lineage for d4c8bb_ (4c8b B:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2546221Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 2546222Protein automated matches [190417] (27 species)
    not a true protein
  7. 2546365Species Human (Homo sapiens) [TaxId:9606] [187294] (946 PDB entries)
  8. 2547568Domain d4c8bb_: 4c8b B: [340417]
    automated match to d5ar8b_
    complexed with 0li, edo

Details for d4c8bb_

PDB Entry: 4c8b (more details), 2.75 Å

PDB Description: structure of the kinase domain of human ripk2 in complex with ponatinib
PDB Compounds: (B:) receptor-interacting serine/threonine-protein kinase 2

SCOPe Domain Sequences for d4c8bb_:

Sequence, based on SEQRES records: (download)

>d4c8bb_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
alptipyhkladlrylsrgasgtvssarhadwrvqvavkhlhihtplldserkdvlreae
ilhkarfsyilpilgicnepeflgivteympngslnellhrkteypdvawplrfrilhei
algvnylhnmtppllhhdlktqnilldnefhvkiadfglskwcmmslsqsrssksapegg
tiiymppenyepgqksrasikhdiysyavitwevlsrkqpfedvtnplqimysvsqghrp
vineeslpydiphrarmisliesgwaqnpderpsflkclielepvlrtfeeitfleaviq
lkktklqs

Sequence, based on observed residues (ATOM records): (download)

>d4c8bb_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
alptipyhkladlrylsrgasgtvssarhadwrvqvavkhllldserkdvlreaeilhka
rfsyilpilgicnepeflgivteympngslnellhrkteypdvawplrfrilheialgvn
ylhnmtppllhhdlktqnilldnefhvkiadfgtiiymppenyepgqksrasikhdiysy
avitwevlsrkqpfedvtnplqimysvsqghrpvineeslpydiphrarmisliesgwaq
npderpsflkclielepvlrtfeeitfleaviqlkktklqs

SCOPe Domain Coordinates for d4c8bb_:

Click to download the PDB-style file with coordinates for d4c8bb_.
(The format of our PDB-style files is described here.)

Timeline for d4c8bb_: