Lineage for d5op6a_ (5op6 A:)

  1. Root: SCOPe 2.06
  2. 2021373Class b: All beta proteins [48724] (177 folds)
  3. 2080271Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
    one turn of helix is made by two pairs of antiparallel strands linked with short turns
    has appearance of a sandwich of distinct architecture and jelly-roll topology
  4. 2081124Superfamily b.82.2: Clavaminate synthase-like [51197] (16 families) (S)
    Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold
  5. 2081311Family b.82.2.6: Hypoxia-inducible factor HIF ihhibitor (FIH1) [82194] (1 protein)
  6. 2081312Protein Hypoxia-inducible factor HIF ihhibitor (FIH1) [82195] (1 species)
  7. 2081313Species Human (Homo sapiens) [TaxId:9606] [82196] (34 PDB entries)
  8. 2081343Domain d5op6a_: 5op6 A: [340273]
    automated match to d3p3na_
    protein/DNA complex; complexed with a0w, gol, so4, zn

Details for d5op6a_

PDB Entry: 5op6 (more details), 2.45 Å

PDB Description: factor inhibiting hif (fih) in complex with zinc and gsk128863
PDB Compounds: (A:) Hypoxia-inducible factor 1-alpha inhibitor

SCOPe Domain Sequences for d5op6a_:

Sequence, based on SEQRES records: (download)

>d5op6a_ b.82.2.6 (A:) Hypoxia-inducible factor HIF ihhibitor (FIH1) {Human (Homo sapiens) [TaxId: 9606]}
epreeagalgpawdesqlrsysfptrpiprlsqsdpraeelieneepvvltdtnlvypal
kwdleylqenigngdfsvysasthkflyydekkmanfqnfkprsnreemkfhefveklqd
iqqrggeerlylqqtlndtvgrkivmdflgfnwnwinkqqgkrgwgqltsnllligmegn
vtpahydeqqnffaqikgykrcilfppdqfeclypypvhhpcdrqsqvdfdnpdyerfpn
fqnvvgyetvvgpgdvlyipmywwhhiesllnggititvnfwykgaptpkrieyplkahq
kvaimrniekmlgealgnpqevgpllntmikgryn

Sequence, based on observed residues (ATOM records): (download)

>d5op6a_ b.82.2.6 (A:) Hypoxia-inducible factor HIF ihhibitor (FIH1) {Human (Homo sapiens) [TaxId: 9606]}
epreeagalgpawdesqlrsysfptrpiprlsqsdpraeelieneepvvltdtnlvypal
kwdleylqenigngdfsvysasthkflyydekkmanfqnfkpnreemkfhefveklqdiq
qrggeerlylqqtlndtvgrkivmdflgfnwnwinkqqgkrgwgqltsnllligmegnvt
pahydeqqnffaqikgykrcilfppdqfeclypypvhhpcdrqsqvdfdnpdyerfpnfq
nvvgyetvvgpgdvlyipmywwhhiesllnggititvnfwykgaptpkrieyplkahqkv
aimrniekmlgealgnpqevgpllntmikgryn

SCOPe Domain Coordinates for d5op6a_:

Click to download the PDB-style file with coordinates for d5op6a_.
(The format of our PDB-style files is described here.)

Timeline for d5op6a_: