SCOPe 2.06: Domain d5tc6a_: 5tc6 A:

Lineage for d5tc6a_ (5tc6 A:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.56: Phosphorylase/hydrolase-like [53162] (8 superfamilies)
   core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops

4. Superfamily c.56.2: Purine and uridine phosphorylases [53167] (2 families)
   complex architecture; contains mixed beta-sheet of 8 strands, order 23415867, strands 3, 6 & 7 are antiparallel to the rest; and barrel, closed; n=5, S=8

5. Family c.56.2.1: Purine and uridine phosphorylases [53168] (7 proteins)

6. Protein 5'-deoxy-5'-methylthioadenosine phosphorylase [53174] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [53175] (13 PDB entries)
   Uniprot Q13126

8. Domain d5tc6a_: 5tc6 A: [340054]
   automated match to d1cb0a_
   complexed with 7a6, cl, gol, na, po4

Details for d5tc6a_

PDB Entry: 5tc6, 1.48 Å

PDB Description: crystal structure of human 5'-deoxy-5'-methylthioadenosine phosphorylase in complex with propylthio-immucillin-a

PDB Compounds: (A:) S-methyl-5'-thioadenosine phosphorylase

SCOPe Domain Sequences for d5tc6a_:

Sequence; same for both SEQRES and ATOM records:

>d5tc6a_ c.56.2.1 (A:) 5'-deoxy-5'-methylthioadenosine phosphorylase {Human (Homo sapiens) [TaxId: 9606]}
avkigiiggtglddpeilegrtekyvdtpfgkpsdalilgkiknvdcvllarhgrqhtim
pskvnyqaniwalkeegcthvivttacgslreeiqpgdiviidqfidrttmrpqsfydgs
hscargvchipmaepfcpktrevlietakklglrchskgtmvtiegprfssraesfmfrt
wgadvinmttvpevvlakeagicyasiamatdydcwkeheeavsvdrvlktlkenankak
slllttipqigstewsetlhnlknmaqfsvllp

Timeline for d5tc6a_:

• d5tc6a_ is new in SCOPe 2.06-stable
  
• d5tc6a_ appears in SCOPe 2.07
  
• d5tc6a_ appears in the current release, SCOPe 2.08