SCOPe 2.08: Domain d5x0ra_: 5x0r A:

Lineage for d5x0ra_ (5x0r A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Pregnane x receptor, PXR [63624] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63625] (32 PDB entries)

8. Domain d5x0ra_: 5x0r A: [339900]
   automated match to d1m13a_
   complexed with 4wh

Details for d5x0ra_

PDB Entry: 5x0r, 2.67 Å

PDB Description: crystal structure of pxr lbd complexed with sjb7

PDB Compounds: (A:) Nuclear receptor subfamily 1 group I member 2

SCOPe Domain Sequences for d5x0ra_:

Sequence, based on SEQRES records:

>d5x0ra_ a.123.1.1 (A:) Pregnane x receptor, PXR {Human (Homo sapiens) [TaxId: 9606]}
glteeqrmmirelmdaqmktfdttfshfknfrlpgvlssgcelpeslqapsreeaakwsq
vrkdlcslkvslqlrgedgsvwnykppadsggkeifsllphmadmstymfkgiisfakvi
syfrdlpiedqisllkgaafelcqlrfntvfnaetgtwecgrlsycledtaggfqqllle
pmlkfhymlkklqlheeeyvlmqaislfspdrpgvlqhrvvdqlqeqfaitlksyiecnr
pqpahrflflkimamltelrsinaqhtqrllriqdihpfatplmqelfgit

Sequence, based on observed residues (ATOM records):

>d5x0ra_ a.123.1.1 (A:) Pregnane x receptor, PXR {Human (Homo sapiens) [TaxId: 9606]}
glteeqrmmirelmdaqmktfdttfshfknfrlpgvvslqlrgedgsvwnykppasllph
madmstymfkgiisfakvisyfrdlpiedqisllkgaafelcqlrfntvfnaetgtwecg
rlsyclllepmlkfhymlkklqlheeeyvlmqaislfspdrpgvlqhrvvdqlqeqfait
lksyiecnrahrflflkimamltelrsinaqhtqrllriqdihpfatplmqelfgit

Timeline for d5x0ra_:

• d5x0ra_ first appeared in SCOPe 2.06
  
• d5x0ra_ appears in SCOPe 2.07