Lineage for d5vgid_ (5vgi D:)

  1. Root: SCOPe 2.06
  2. 2021373Class b: All beta proteins [48724] (177 folds)
  3. 2080271Fold b.82: Double-stranded beta-helix [51181] (7 superfamilies)
    one turn of helix is made by two pairs of antiparallel strands linked with short turns
    has appearance of a sandwich of distinct architecture and jelly-roll topology
  4. 2081124Superfamily b.82.2: Clavaminate synthase-like [51197] (16 families) (S)
    Iron and ketoglutarate-dependent enzymes; elaborated version of this common fold
  5. 2081473Family b.82.2.14: Histone demethylase core [254153] (4 proteins)
    Jumonji domain; Pfam PF02375 (JmjN) and Pfam PF02373 (JmjC); relationship to FIH1 (b.82.2.6) described in PubMed 16983801
  6. 2081477Protein JMJD2A core [254342] (1 species)
  7. 2081478Species Human (Homo sapiens) [TaxId:9606] [254775] (41 PDB entries)
  8. 2081522Domain d5vgid_: 5vgi D: [339675]
    automated match to d4v2wb_
    complexed with 9dj, ni, zn

Details for d5vgid_

PDB Entry: 5vgi (more details), 2.07 Å

PDB Description: crystal structure of kdm4 with the small molecule inhibitor qc6352
PDB Compounds: (D:) lysine-specific demethylase 4a

SCOPe Domain Sequences for d5vgid_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5vgid_ b.82.2.14 (D:) JMJD2A core {Human (Homo sapiens) [TaxId: 9606]}
npsarimtfyptmeefrnfsryiayiesqgahraglakvvppkewkprasyddiddlvip
apiqqlvtgqsglftqyniqkkamtvrefrkiansdkyctprysefeelerkywknltfn
ppiygadvngtlyekhvdewnigrlrtildlvekesgitiegvntpylyfgmwktsfawh
tedmdlysinylhfgepkswysvppehgkrlerlakgffpgsaqsceaflrhkmtlispl
mlkkygipfdkvtqeagefmitfpygyhagfnhgfncaestnfatrrwieygkqavlcsc
rkdmvkismdvfvrkfqperyklwkagkdntvidhtlptpeaaef

SCOPe Domain Coordinates for d5vgid_:

Click to download the PDB-style file with coordinates for d5vgid_.
(The format of our PDB-style files is described here.)

Timeline for d5vgid_: