SCOPe 2.06: Domain d5v9la1: 5v9l A:1-168

Lineage for d5v9la1 (5v9l A:1-168)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (79 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein automated matches [190047] (29 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186768] (179 PDB entries)

8. Domain d5v9la1: 5v9l A:1-168 [338378]
   Other proteins in same PDB: d5v9la2, d5v9lb2, d5v9lc2
   automated match to d4obea_
   complexed with 91d, gdp, mg

Details for d5v9la1

PDB Entry: 5v9l, 1.98 Å

PDB Description: kras g12c in bound to quinazoline based switch ii pocket (swiip) binder

PDB Compounds: (A:) GTPase KRas

SCOPe Domain Sequences for d5v9la1:

Sequence; same for both SEQRES and ATOM records:

>d5v9la1 c.37.1.8 (A:1-168) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mteyklvvvgacgvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtag
qeeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcdl
psrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhke

Timeline for d5v9la1:

• d5v9la1 is new in SCOPe 2.06-stable
  
• d5v9la1 appears in SCOPe 2.07
  
• d5v9la1 appears in the current release, SCOPe 2.08