SCOPe 2.08: Domain d5xkmc1: 5xkm C:578-917

Lineage for d5xkmc1 (5xkm C:578-917)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (9 families)

5. Family a.211.1.0: automated matches [191566] (1 protein)
   not a true family

6. Protein automated matches [190983] (12 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188676] (139 PDB entries)

8. Domain d5xkmc1: 5xkm C:578-917 [338053]
   Other proteins in same PDB: d5xkmb2, d5xkmc2
   automated match to d4d09a_
   complexed with 87r, mg, zn

Details for d5xkmc1

PDB Entry: 5xkm, 2.16 Å

PDB Description: crystal structure of human phosphodiesterase 2a in complex with 6- methyl-n-(1-(4-(trifluoromethoxy)phenyl)propyl)pyrazolo[1,5- a]pyrimidine-3-carboxamide

PDB Compounds: (C:) cGMP-dependent 3',5'-cyclic phosphodiesterase

SCOPe Domain Sequences for d5xkmc1:

Sequence; same for both SEQRES and ATOM records:

>d5xkmc1 a.211.1.0 (C:578-917) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sddeytkllhdgiqpvaaidsnfasftytprslpeddtsmailsmlqdmnfinnykidcp
tlarfclmvkkgyrdppyhnwmhafsvshfcyllyknleltnyledieifalfiscmchd
ldhrgtnnsfqvasksvlaalyssegsvmerhhfaqaiailnthgcnifdhfsrkdyqrm
ldlmrdiilatdlahhlrifkdlqkmaevgydrnnkqhhrlllcllmtscdlsdqtkgwk
ttrkiaeliykeffsqgdlekamgnrpmemmdrekayipelqisfmehiampiykllqdl
fpkaaelyervasnrehwtkvshkftirglpsnnsldfld

Timeline for d5xkmc1:

• d5xkmc1 first appeared in SCOPe 2.06
  
• d5xkmc1 appears in SCOPe 2.07