SCOPe 2.06: Domain d5l21a2: 5l21 A:1093-1296

Lineage for d5l21a2 (5l21 A:1093-1296)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.42: beta-Trefoil [50352] (8 superfamilies)
   barrel, closed; n=6, S=12; and a hairpin triplet; meander
   duplication: has internal pseudo threefold symmetry

4. Superfamily b.42.4: STI-like [50386] (3 families)

5. Family b.42.4.2: Clostridium neurotoxins, C-terminal domain [50399] (3 proteins)
   overall fold is very similar to that of the STI family
   automatically mapped to Pfam PF07951

6. Protein automated matches [229100] (4 species)
   not a true protein

7. Species Clostridium botulinum [TaxId:441771] [337544] (1 PDB entry)

8. Domain d5l21a2: 5l21 A:1093-1296 [337545]
   Other proteins in same PDB: d5l21a1, d5l21a3, d5l21b_
   automated match to d3btaa2

Details for d5l21a2

PDB Entry: 5l21, 1.68 Å

PDB Description: crystal structure of bont/a receptor binding domain in complex with vhh c2

PDB Compounds: (A:) Botulinum neurotoxin type A

SCOPe Domain Sequences for d5l21a2:

Sequence, based on SEQRES records:

>d5l21a2 b.42.4.2 (A:1093-1296) automated matches {Clostridium botulinum [TaxId: 441771]}
nsgilkdfwgdylqydkpyymlnlydpnkyvdvnnvgirgymylkgprgsvmttniylns
slyrgakfiikkyasgnkdnivrnndrvyinvvvknkeyrlatnasqagvekilsaleip
dvgnlsqvvvmkskndqgitnkckmnlqdnngndigfigfhqfnniaklvasnwynrqie
rssrtlgcswefipvddgwgerpl

Sequence, based on observed residues (ATOM records):

>d5l21a2 b.42.4.2 (A:1093-1296) automated matches {Clostridium botulinum [TaxId: 441771]}
nsgilkdfwgdylqydkpyymlnlydpnkyvdvnnvgirgymylkgprgsvmttniylns
slyrgakfiikkynkdnivrnndrvyinvvvknkeyrlatnasqagvekilsaleipdvg
nlsqvvvmkskndqgitnkckmnlqdnngndigfigfhqfnniaklvasnwynrqierss
rtlgcswefipvddgwgerpl

Timeline for d5l21a2:

• d5l21a2 is new in SCOPe 2.06-stable
  
• d5l21a2 appears in SCOPe 2.07
  
• d5l21a2 appears in the current release, SCOPe 2.08