SCOPe 2.06: Domain d5kyea_: 5kye A:

Lineage for d5kyea_ (5kye A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.9: Ubiquitin carboxyl-terminal hydrolase, UCH [82568] (6 proteins)
   Pfam PF00443

6. Protein automated matches [191167] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [189384] (17 PDB entries)

8. Domain d5kyea_: 5kye A: [337512]
   Other proteins in same PDB: d5kyec_, d5kyed_
   automated match to d1nbfa_
   complexed with epe; mutant

Details for d5kyea_

PDB Entry: 5kye, 1.97 Å

PDB Description: crystal structure of usp7 catalytic domain [h294e] mutant in complex with ubiquitin

PDB Compounds: (A:) Ubiquitin carboxyl-terminal hydrolase 7

SCOPe Domain Sequences for d5kyea_:

Sequence, based on SEQRES records:

>d5kyea_ d.3.1.9 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
khtgyvglknqgatcymnsllqtlfftnqlrkavymmptegddssksvplalqrvfyelq
hsdkpvgtkkltksfgwetldsfmqedvqelcrvlldnvenkmkgtcvegtipklfrgkm
vsyiqckevdyrsdrredyydiqlsikgkknifesfvdyvaveqldgdnkydagehglqe
aekgvkfltlppvlhlqlmrfmydpqtdqnikindrfefpeqlpldeflqktdpkdpany
ilhavlvhsgdnhgghyvvylnpkgdgkwckfdddvvsrctkeeaiehnygghdddlsvr
hctnaymlvyiresklsevlqavtdhdipqqlverlqeekrieaq

Sequence, based on observed residues (ATOM records):

>d5kyea_ d.3.1.9 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
khtgyvglknqgatcymnsllqtlfftnqlrkavymmptegddssksvplalqrvfyelq
hsdkpvgtkkltksfgwetldsfmqedvqelcrvlldnvenkmkgtcvegtipklfrgkm
vsyiqckevdyrsdrredyydiqlsikgkknifesfvdyvaveqldgdnkydagehglqe
aekgvkfltlppvlhlqlmrfmydpqtdqnikindrfefpeqlpldeflqktdpkdpany
ilhavlvhsgdnhgghyvvylnpkgdgkwckfdddvvsrctkeeaiehnygghdddlrhc
tnaymlvyiresklsevlqavtdhdipqqlverlqeekrieaq

Timeline for d5kyea_:

• d5kyea_ is new in SCOPe 2.06-stable
  
• d5kyea_ appears in SCOPe 2.07
  
• d5kyea_ appears in the current release, SCOPe 2.08