SCOPe 2.06: Domain d5u6bc_: 5u6b C:

Lineage for d5u6bc_ (5u6b C:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (25 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (882 PDB entries)

8. Domain d5u6bc_: 5u6b C: [337104]
   Other proteins in same PDB: d5u6bb2, d5u6bd2
   automated match to d4v04b_
   complexed with 7ys

Details for d5u6bc_

PDB Entry: 5u6b, 2.84 Å

PDB Description: structure of the axl kinase domain in complex with a macrocyclic inhibitor

PDB Compounds: (C:) tyrosine-protein kinase receptor ufo

SCOPe Domain Sequences for d5u6bc_:

Sequence, based on SEQRES records:

>d5u6bc_ d.144.1.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
elkeklrdvmvdrhkvalgktlgegefgavmegqlnqddsilkvavktmkiaictrsele
dflseavcmkefdhpnvmrligvcfqgseresfpapvvilpfmkhgdlhsfllysrlgdq
pvylptqmlvkfmadiasgmeylstkrfihrdlaarncmlnenmsvcvadfglskkiyng
dyyrqgriakmpvkwiaiesladrvytsksdvwsfgvtmweiatrgqtpypgvenseiyd
ylrqgnrlkqpadcldglyalmsrcwelnpqdrpsftelredlentlkalppa

Sequence, based on observed residues (ATOM records):

>d5u6bc_ d.144.1.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
elkeklrdvmvdrhkvalgktlgegefgavmegqlnqddsilkvavktmkiaictrsele
dflseavcmkefdhpnvmrligvcfqpapvvilpfmkhgdlhsfllysrlgdqpvylptq
mlvkfmadiasgmeylstkrfihrdlaarncmlnenmsvcvadfglskpvkwiaieslad
rvytsksdvwsfgvtmweiatrgqtpypgvenseiydylrqgnrlkqpadcldglyalms
rcwelnpqdrpsftelredlentlkalppa

Timeline for d5u6bc_:

• d5u6bc_ is new in SCOPe 2.06-stable
  
• d5u6bc_ appears in SCOPe 2.07
  
• d5u6bc_ appears in the current release, SCOPe 2.08