SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5ksic_ (5ksi C:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1976410Fold a.1: Globin-like [46457] (2 superfamilies)
    core: 6 helices; folded leaf, partly opened
  4. 1976411Superfamily a.1.1: Globin-like [46458] (5 families) (S)
  5. 1976488Family a.1.1.2: Globins [46463] (27 protein domains)
    Heme-binding protein
  6. 1976759Protein Hemoglobin, alpha-chain [46486] (24 species)
  7. 1976884Species Human (Homo sapiens) [TaxId:9606] [46487] (249 PDB entries)
    Uniprot P69905 P01922 P01934 P01935
  8. 2293718Domain d5ksic_: 5ksi C: [337019]
    Other proteins in same PDB: d5ksib_, d5ksid_
    automated match to d1irda_
    complexed with dg2, hem, s1p

Details for d5ksic_

PDB Entry: 5ksi (more details), 1.8 Å

PDB Description: crystal structure of deoxygenated hemoglobin in complex with sphingosine phosphate and 2,3-bisphosphoglycerate
PDB Compounds: (C:) Hemoglobin subunit alpha

SCOPe Domain Sequences for d5ksic_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5ksic_ a.1.1.2 (C:) Hemoglobin, alpha-chain {Human (Homo sapiens) [TaxId: 9606]}
vlspadktnvkaawgkvgahageygaealermflsfpttktyfphfdlshgsaqvkghgk
kvadaltnavahvddmpnalsalsdlhahklrvdpvnfkllshcllvtlaahlpaeftpa
vhasldkflasvstvltskyr

SCOPe Domain Coordinates for d5ksic_:

Click to download the PDB-style file with coordinates for d5ksic_.
(The format of our PDB-style files is described here.)

Timeline for d5ksic_:

  • d5ksic_ appears in periodic updates to SCOPe 2.06 starting on 2017-07-27