SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5ku6b_ (5ku6 B:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2067964Fold b.74: Carbonic anhydrase [51068] (1 superfamily)
    single sheet; 10 strands
  4. 2067965Superfamily b.74.1: Carbonic anhydrase [51069] (2 families) (S)
  5. 2067966Family b.74.1.1: Carbonic anhydrase [51070] (2 protein domains)
    automatically mapped to Pfam PF00194
  6. 2067967Protein Carbonic anhydrase [51071] (10 species)
  7. 2068582Species Human (Homo sapiens), isozyme IV [TaxId:9606] [51076] (9 PDB entries)
  8. 2293679Domain d5ku6b_: 5ku6 B: [336980]
    automated match to d1znca_
    complexed with act, gol, mzm, so4, zn

Details for d5ku6b_

PDB Entry: 5ku6 (more details), 1.8 Å

PDB Description: crystal structure for the complex of human carbonic anhydrase iv and methazolamide
PDB Compounds: (B:) Carbonic anhydrase 4

SCOPe Domain Sequences for d5ku6b_:

Sequence, based on SEQRES records: (download)

>d5ku6b_ b.74.1.1 (B:) Carbonic anhydrase {Human (Homo sapiens), isozyme IV [TaxId: 9606]}
hwcyevqaessnypclvpvkwggncqkdrqspinivttkakvdkklgrfffsgydkkqtw
tvqnnghsvmmllenkasisggglpapyqakqlhlhwsdlpykgsehsldgehfamemhi
vhekekgtsrnvkeaqdpedeiavlaflveagtqvnegfqplvealsnipkpemsttmae
sslldllpkeeklrhyfrylgslttptcdekvvwtvfrepiqlhreqilafsqklyydke
qtvsmkdnvrplqqlgqrtviks

Sequence, based on observed residues (ATOM records): (download)

>d5ku6b_ b.74.1.1 (B:) Carbonic anhydrase {Human (Homo sapiens), isozyme IV [TaxId: 9606]}
hwcyevqaessnypclvpvkwggncqkdrqspinivttkakvdkklgrfffsgydkkqtw
tvqnnghsvmmllenkasisggglpapyqakqlhlhwsdlpykgsehsldgehfamemhi
vhekekgtdpedeiavlaflveagtqvnegfqplvealsnipkpemsttmaesslldllp
keeklrhyfrylgslttptcdekvvwtvfrepiqlhreqilafsqklyydkeqtvsmkdn
vrplqqlgqrtviks

SCOPe Domain Coordinates for d5ku6b_:

Click to download the PDB-style file with coordinates for d5ku6b_.
(The format of our PDB-style files is described here.)

Timeline for d5ku6b_:

  • d5ku6b_ appears in periodic updates to SCOPe 2.06 starting on 2017-07-27