SCOP 1.71: Domain d1c6va_: 1c6v A:

Lineage for d1c6va_ (1c6v A:)

1. Root: SCOP 1.71

2. Class c: Alpha and beta proteins (a/b) [51349] (134 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.3: Ribonuclease H-like [53098] (10 families)
   consists of one domain of this fold

5. Family c.55.3.2: Retroviral integrase, catalytic domain [53107] (1 protein)

6. Protein Retroviral integrase, catalytic domain [53108] (3 species)

7. Species Simian immunodeficiency virus [53111] (1 PDB entry)

8. Domain d1c6va_: 1c6v A: [33672]
   Other proteins in same PDB: d1c6vx_

Details for d1c6va_

PDB Entry: 1c6v, 3 Å

PDB Description: siv integrase (catalytic domain + dna biding domain comprising residues 50-293) mutant with phe 185 replaced by his (f185h)

SCOP Domain Sequences for d1c6va_:

Sequence, based on SEQRES records:

>d1c6va_ c.55.3.2 (A:) Retroviral integrase, catalytic domain {Simian immunodeficiency virus}
nsdlgtwqmdcthlegkivivavhvasgfieaevipqetgrqtalfllklagrwpithlh
tdnganfasqevkmvawwagiehtfgvpynpqsqgvveamnhhlknqidrireqansvet
ivlmavhcmnhkrrggigdmtpaerlinmitteqeiqfq

Sequence, based on observed residues (ATOM records):

>d1c6va_ c.55.3.2 (A:) Retroviral integrase, catalytic domain {Simian immunodeficiency virus}
nsdlgtwqmdcthlegkivivavhvasgfieaevipqetgrqtalfllklagrwpithlh
tdnganfasqevkmvawwagiehtfgeamnhhlknqidrireqansvetivlmavhcmnh
krrggigdmtpaerlinmitteqeiqfq

Timeline for d1c6va_:

• d1c6va_ first appeared (with stable ids) in SCOP 1.55
  
• d1c6va_ appears in SCOP 1.69
  
• d1c6va_ appears in SCOP 1.73
  
• d1c6va_ appears in the current release, SCOPe 2.08