SCOPe 2.08: Domain d5ky6a_: 5ky6 A:

Lineage for d5ky6a_ (5ky6 A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.10: Aldolase [51569] (9 families)
   Common fold covers whole protein structure

5. Family c.1.10.1: Class I aldolase [51570] (13 proteins)
   the catalytic lysine forms schiff-base intermediate with substrate
   possible link between the aldolase superfamily and the phosphate-binding beta/alpha barrels

6. Protein Fructose-1,6-bisphosphate aldolase [51576] (11 species)

7. Species Human (Homo sapiens), muscle isozyme [TaxId:9606] [51577] (4 PDB entries)

8. Domain d5ky6a_: 5ky6 A: [336081]
   automated match to d2alda_

Details for d5ky6a_

PDB Entry: 5ky6, 1.94 Å

PDB Description: human muscle fructose-1,6-bisphosphate aldolase

PDB Compounds: (A:) Fructose-bisphosphate aldolase A

SCOPe Domain Sequences for d5ky6a_:

Sequence, based on SEQRES records:

>d5ky6a_ c.1.10.1 (A:) Fructose-1,6-bisphosphate aldolase {Human (Homo sapiens), muscle isozyme [TaxId: 9606]}
pyqypaltpeqkkelsdiahrivapgkgilaadestgsiakrlqsigtenteenrrfyrq
llltaddrvnpciggvilfhetlyqkaddgrpfpqvikskggvvgikvdkgvvplagtng
etttqgldglsercaqykkdgadfakwrcvlkigehtpsalaimenanvlaryasicqqn
givpivepeilpdgdhdlkrcqyvtekvlaavykalsdhhiylegtllkpnmvtpghact
qkfsheeiamatvtalrrtvppavtgitflsggqseeeasinlnainkcpllkpwaltfs
ygralqasalkawggkkenlkaaqeeyvkralanslacqgkyt

Sequence, based on observed residues (ATOM records):

>d5ky6a_ c.1.10.1 (A:) Fructose-1,6-bisphosphate aldolase {Human (Homo sapiens), muscle isozyme [TaxId: 9606]}
pyqypaltpeqkkelsdiahrivapgkgilaadestgsianteenrrfyrqllltaddrv
npciggvilfhetlyqkaddgrpfpqvikskggvvgikvdkgvvplagtngetttqgldg
lsercaqykkdgadfakwrcvlkigehtpsalaimenanvlaryasicqqngivpivepe
ilpdgdhdlkrcqyvtekvlaavykalsdhhiylegtllkpnmvtpghactqkfsheeia
matvtalrrtvppavtgitflsggqseeeasinlnainkcpllkpwaltfsygralqasa
lkaaqeeyvkralanslacqgkyt

Timeline for d5ky6a_:

• d5ky6a_ first appeared in SCOPe 2.06
  
• d5ky6a_ appears in SCOPe 2.07