SCOPe 2.04: Domain d1vrua1: 1vru A:430-539

Lineage for d1vrua1 (1vru A:430-539)

1. Root: SCOPe 2.04

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.3: Ribonuclease H-like [53098] (15 families)
   consists of one domain of this fold

5. Family c.55.3.1: Ribonuclease H [53099] (5 proteins)

6. Protein HIV RNase H (Domain of reverse transcriptase) [53105] (3 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [53106] (102 PDB entries)
   Uniprot P04585 159-692 # chain A coverage; chain B is shorter: 162-582 ! Uniprot P03366 186-725 # chain A coverage; chain B coverage: 156-584 ! Uniprot P04585 158-698 # chain A coverage; chain B is shorter: 159-595

8. Domain d1vrua1: 1vru A:430-539 [33575]
   Other proteins in same PDB: d1vrua2, d1vrub_
   complexed with aap

Details for d1vrua1

PDB Entry: 1vru, 2.4 Å

PDB Description: high resolution structures of hiv-1 rt from four rt-inhibitor complexes

PDB Compounds: (A:) hiv-1 reverse transcriptase

SCOPe Domain Sequences for d1vrua1:

Sequence, based on SEQRES records:

>d1vrua1 c.55.3.1 (A:430-539) HIV RNase H (Domain of reverse transcriptase) {Human immunodeficiency virus type 1 [TaxId: 11676]}
ekepivgaetfyvdgaanretklgkagyvtnrgrqkvvtltdttnqktelqaiylalqds
glevnivtdsqyalgiiqaqpdqseselvnqiieqlikkekvylawvpah

Sequence, based on observed residues (ATOM records):

>d1vrua1 c.55.3.1 (A:430-539) HIV RNase H (Domain of reverse transcriptase) {Human immunodeficiency virus type 1 [TaxId: 11676]}
ekepivgaetfyvdagyvtnrgrqkvvtltdttnqktelqaiylalqdsglevnivtdsq
yalgiiqaqpdqseselvnqiieqlikkekvylawvpah

Timeline for d1vrua1:

• d1vrua1 first appeared (with stable ids) in SCOP 1.55
  
• d1vrua1 appears in SCOPe 2.03
  
• d1vrua1 appears in SCOPe 2.05
  
• d1vrua1 appears in the current release, SCOPe 2.08