SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Species: Foot-and-mouth disease virus - type o [TaxId: 12118]

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2075417Fold b.121: Nucleoplasmin-like/VP (viral coat and capsid proteins) [88632] (7 superfamilies)
    sandwich; 8 strands in 2 sheets; jelly-roll; some members can have additional 1-2 strands
    characteristic interaction between the domains of this fold allows the formation of five-fold and pseudo six-fold assemblies
  4. 2075626Superfamily b.121.4: Positive stranded ssRNA viruses [88633] (10 families) (S)
  5. 2075627Family b.121.4.1: Picornaviridae-like VP (VP1, VP2, VP3 and VP4) [88634] (10 protein domains)
    the order of the chains N-VP0-VP3-VP1-C is as in the polyprotein; VP0 is cleaved later upon capsid assembly to VP4 and VP2
    there is a different order in the shuffled genome of insect picorna-like proteins (Cricket paralysis virus)
  6. 2075905Protein automated matches [190854] (13 species)
    not a true protein
  7. 2292138Species Foot-and-mouth disease virus - type o [TaxId:12118] [335439] (1 PDB entry)

PDB entry in Species: Foot-and-mouth disease virus - type o [TaxId: 12118]:

More info for Species Foot-and-mouth disease virus - type o [TaxId:12118] from b.121.4.1 automated matches

Timeline for Species Foot-and-mouth disease virus - type o [TaxId:12118] from b.121.4.1 automated matches:

  • Species Foot-and-mouth disease virus - type o [TaxId:12118] from b.121.4.1 automated matches appears in periodic updates to SCOPe 2.06 starting on 2017-06-15