SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5h0wa1 (5h0w A:11-124)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2034780Fold b.3: Prealbumin-like [49451] (7 superfamilies)
    sandwich; 7 strands in 2 sheets, greek-key
    variations: some members have additional 1-2 strands to common fold
  4. 2035040Superfamily b.3.4: Transthyretin (synonym: prealbumin) [49472] (2 families) (S)
  5. 2035041Family b.3.4.1: Transthyretin (synonym: prealbumin) [49473] (2 protein domains)
    automatically mapped to Pfam PF00576
  6. 2035609Protein automated matches [190376] (1 species)
    not a true protein
  7. 2035610Species Human (Homo sapiens) [TaxId:9606] [187223] (16 PDB entries)
  8. 2292042Domain d5h0wa1: 5h0w A:11-124 [335343]
    Other proteins in same PDB: d5h0wa2
    automated match to d5ezpe_
    complexed with so4

Details for d5h0wa1

PDB Entry: 5h0w (more details), 1.9 Å

PDB Description: crystal structure of h88f mutated human transthyretin
PDB Compounds: (A:) Transthyretin

SCOPe Domain Sequences for d5h0wa1:

Sequence, based on SEQRES records: (download)

>d5h0wa1 b.3.4.1 (A:11-124) automated matches {Human (Homo sapiens) [TaxId: 9606]}
plmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiyk
veidtksywkalgispffehaevvftandsgprrytiaallspysysttavvtn

Sequence, based on observed residues (ATOM records): (download)

>d5h0wa1 b.3.4.1 (A:11-124) automated matches {Human (Homo sapiens) [TaxId: 9606]}
plmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiyk
veidtksywkalgispffehaevvftanprrytiaallspysysttavvtn

SCOPe Domain Coordinates for d5h0wa1:

Click to download the PDB-style file with coordinates for d5h0wa1.
(The format of our PDB-style files is described here.)

Timeline for d5h0wa1:

  • d5h0wa1 appears in periodic updates to SCOPe 2.06 starting on 2017-06-15

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Domains from same chain:
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d5h0wa2