SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5vcga_ (5vcg A:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2004931Fold a.104: Cytochrome P450 [48263] (1 superfamily)
    multihelical
  4. 2004932Superfamily a.104.1: Cytochrome P450 [48264] (2 families) (S)
  5. 2004933Family a.104.1.1: Cytochrome P450 [48265] (23 protein domains)
  6. 2005432Protein automated matches [190068] (9 species)
    not a true protein
  7. 2005449Species Human (Homo sapiens) [TaxId:9606] [189507] (35 PDB entries)
  8. 2291743Domain d5vcga_: 5vcg A: [335044]
    automated match to d1w0ea_
    complexed with 08y, gol, hem

Details for d5vcga_

PDB Entry: 5vcg (more details), 2.2 Å

PDB Description: crystal structure of the cysteine depleted cyp3a4 bound to bromoergocryptine
PDB Compounds: (A:) cytochrome p450 3a4

SCOPe Domain Sequences for d5vcga_:

Sequence, based on SEQRES records: (download)

>d5vcga_ a.104.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
hshglfkklgipgptplpflgnilsyhkgfamfdmemhkkygkvwgfydgqqpvlaitdp
dmiktvlvkeaysvftnrrpfgpvgfmksaisiaedeewkrlrsllsptftsgklkemvp
iiaqygdvlvrnlrreaetgkpvtlkdvfgaysmdvitstsfgvnidslnnpqdpfvent
kkllrfdfldpfflsitvfpflipilevlnitvfprevtnflrksvkrmkesrledtqkh
rvdflqlmidsqnsketeshkalsdlelvaqsiififagyettssvlsfimyelathpdv
qqklqeeidavlpnkapptydtvlqmeyldmvvnetlrlfpiamrlervakkdveingmf
ipkgvvvmipsyalhrdpkywtepekflperfskknkdnidpyiytpfgsgprncigmrf
almnmklalirvlqnfsfkpsketqiplklslggllqpekpvvlkvesrd

Sequence, based on observed residues (ATOM records): (download)

>d5vcga_ a.104.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
hshglfkklgipgptplpflgnilsyhkgfamfdmemhkkygkvwgfydgqqpvlaitdp
dmiktvlvkeaysvftnrrpfgpvgfmksaisiaedeewkrlrsllsptftsgklkemvp
iiaqygdvlvrnlrreaetgkpvtlkdvfgaysmdvitstsfgvnidslnnpqdpfvent
kkllrfdfldpfflsitvfpflipilevlnitvfprevtnflrksvkrmkesrledhrvd
flqlmidsqnskalsdlelvaqsiififagyettssvlsfimyelathpdvqqklqeeid
avlpnkapptydtvlqmeyldmvvnetlrlfpiamrlervakkdveingmfipkgvvvmi
psyalhrdpkywtepekflperfskknkdnidpyiytpfgsgprncigmrfalmnmklal
irvlqnfsfkpsketqiplklslggllqpekpvvlkvesrd

SCOPe Domain Coordinates for d5vcga_:

Click to download the PDB-style file with coordinates for d5vcga_.
(The format of our PDB-style files is described here.)

Timeline for d5vcga_:

  • d5vcga_ appears in periodic updates to SCOPe 2.06 starting on 2017-06-01