SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for d5tcja_ (5tcj A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2078560Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2079053Superfamily c.1.2: Ribulose-phoshate binding barrel [51366] (7 families) (S)
  5. 2079793Family c.1.2.0: automated matches [191350] (1 protein)
    not a true family
  6. 2079794Protein automated matches [190292] (34 species)
    not a true protein
  7. 2291594Species Mycobacterium tuberculosis [TaxId:83332] [334895] (5 PDB entries)
  8. 2291726Domain d5tcja_: 5tcj A: [335027]
    automated match to d2ekcb_
    complexed with 79v, cs, fmt, mli, p1t

Details for d5tcja_

PDB Entry: 5tcj (more details), 2.4 Å

PDB Description: crystal structure of tryptophan synthase from m. tuberculosis - aminoacrylate and brd4592-bound form
PDB Compounds: (A:) tryptophan synthase alpha chain

SCOPe Domain Sequences for d5tcja_:

Sequence, based on SEQRES records: (download)

>d5tcja_ c.1.2.0 (A:) automated matches {Mycobacterium tuberculosis [TaxId: 83332]}
easrlgpvfdscrannraaligylptgypdvpasvaamtalvesgcdiievgvpysdpgm
dgptiarateaalrggvrvrdtlaaveaisiaggravvmtywnpvlrygvdafardlaaa
gglglitpdlipdeaqqwlaaseehrldriflvapsstperlaatveasrgfvyaastmg
vtgardavsqaapelvgrvkavsdipvgvglgvrsraqaaqiaqyadgvivgsalvtalt
eglprlraltgelaagvrlg

Sequence, based on observed residues (ATOM records): (download)

>d5tcja_ c.1.2.0 (A:) automated matches {Mycobacterium tuberculosis [TaxId: 83332]}
easrlgpvfdscrannraaligylptgypdvpasvaamtalvesgcdiievgvpysdpgm
dgptiarateaalrggvrvrdtlaaveaisiaggravvmtywnpvlrygvdafardlaaa
gglglitpdlipdeaqqwlaaseehrldriflvapsstperlaatveasrgfvyaassqa
apelvgrvkavsdipvgvglgvrsraqaaqiaqyadgvivgsalvtalteglprlraltg
elaagvrlg

SCOPe Domain Coordinates for d5tcja_:

Click to download the PDB-style file with coordinates for d5tcja_.
(The format of our PDB-style files is described here.)

Timeline for d5tcja_:

  • d5tcja_ appears in periodic updates to SCOPe 2.06 starting on 2017-06-01