Lineage for d5mima1 (5mim A:109-442)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2873305Fold c.41: Subtilisin-like [52742] (1 superfamily)
    3 layers: a/b/a, parallel beta-sheet of 7 strands, order 2314567; left-handed crossover connection between strands 2 & 3
  4. 2873306Superfamily c.41.1: Subtilisin-like [52743] (3 families) (S)
  5. 2873307Family c.41.1.1: Subtilases [52744] (15 proteins)
  6. 2873644Protein automated matches [190073] (16 species)
    not a true protein
  7. 2873743Species Human (Homo sapiens) [TaxId:9606] [238473] (13 PDB entries)
  8. 2873752Domain d5mima1: 5mim A:109-442 [334209]
    Other proteins in same PDB: d5mima2, d5mima3
    automated match to d1p8ja2
    complexed with 1n, ca, cl, na

Details for d5mima1

PDB Entry: 5mim (more details), 1.9 Å

PDB Description: xray structure of human furin bound with the 2,5-dideoxystreptamine derived small molecule inhibitor 1n
PDB Compounds: (A:) Furin

SCOPe Domain Sequences for d5mima1:

Sequence; same for both SEQRES and ATOM records: (download)

>d5mima1 c.41.1.1 (A:109-442) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vyqeptdpkfpqqwylsgvtqrdlnvkaawaqgytghgivvsilddgieknhpdlagnyd
pgasfdvndqdpdpqprytqmndnrhgtrcagevaavanngvcgvgvaynariggvrmld
gevtdavearslglnpnhihiysaswgpeddgktvdgparlaeeaffrgvsqgrgglgsi
fvwasgnggrehdscncdgytnsiytlsissatqfgnvpwyseacsstlattyssgnqne
kqivttdlrqkcteshtgtsasaplaagiialtleanknltwrdmqhlvvqtskpahlna
ndwatngvgrkvshsygyglldagamvalaqnwt

SCOPe Domain Coordinates for d5mima1:

Click to download the PDB-style file with coordinates for d5mima1.
(The format of our PDB-style files is described here.)

Timeline for d5mima1: