SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Species: Naegleria fowleri [TaxId: 5763]

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2090218Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
    The nucleotide-binding modes of this and the next two folds/superfamilies are similar
  4. 2090219Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families) (S)
  5. 2090553Family c.2.1.2: Tyrosine-dependent oxidoreductases [51751] (71 protein domains)
    also known as short-chain dehydrogenases and SDR family
    parallel beta-sheet is extended by 7th strand, order 3214567; left-handed crossover connection between strands 6 and 7
  6. 2091795Protein automated matches [190085] (51 species)
    not a true protein
  7. 2289498Species Naegleria fowleri [TaxId:5763] [332799] (1 PDB entry)

PDB entry in Species: Naegleria fowleri [TaxId: 5763]:

More info for Species Naegleria fowleri [TaxId:5763] from c.2.1.2 automated matches

Timeline for Species Naegleria fowleri [TaxId:5763] from c.2.1.2 automated matches:

  • Species Naegleria fowleri [TaxId:5763] from c.2.1.2 automated matches appears in periodic updates to SCOPe 2.06 starting on 2017-04-06